Evidence map›Paper›PMID 40857484›Full record

ArticleIEEE/ASME transactions on mechatronics : a joint publication of the IEEE Industrial Electronics Society and the ASME Dynamic Systems and Control Division2025

Integrating Optics and Parametrically-Resonant Micro-Scanner Design for Large Working Distance Implantable Microscopy.

Tayebeh Sahraeibelverdi, Ahmad Shirazi, Miki Lee, Haijun Li, Sung Eun Kwon, Thomas D Wang, Kenn R Oldham

Abstract read
In one paragraph

Article in IEEE/ASME transactions on mechatronics : a joint publication of the IEEE Industrial Electronics Society and the ASME Dynamic Systems and Control Division, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Compact, scan-pattern-switchable 2D piezoelectric MEMS mirror with 1D addressable scanning.Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tayebeh SahraeibelverdiDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109 USA.
Ahmad ShiraziUniversity of Michigan, Ann Arbor, MI 48109 USA; Apple Inc., Cupertino, CA 95014 USA.
Miki LeeDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI 48109 USA; Allen Institute, Seattle, WA 98109 USA.ORCID 0000-0003-2634-5341
Haijun LiDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI 48109 USA.ORCID 0000-0001-9887-7342
Sung Eun KwonDepartment of Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109 USA; AbbVie Inc., Chicago, IL 60064 USA.
Thomas D WangDepartments of Internal Medicine, Biomedical Engineering, and Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109 USA.
Kenn R OldhamDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109 USA.ORCID 0000-0002-5962-3056

Funding

Microsystems imaging system for epithelial-derived cancer heterogeneityU01EB028235 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI OLDHAM, KENN R, WANG, THOMAS D · 2019 to 2023
$2.9M
Implantable 3D fluorescence imaging with high-speed, addressable laser scanning in moving miceRF1NS131063 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI OLDHAM, KENN R · 2023 to 2023
$1.7M
Multiplexed Multi-Modal Endoscopic Imaging of Cancer BiomarkersU01CA189291 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WANG, THOMAS D · 2015 to 2018
$1.4M
Multi-Photon endomicroscope for real-time in vivo vertical sectioningR01EB020644 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI OLDHAM, KENN R · 2015 to 2018
$1.3M
NCI NIH HHS U01 CA189291NIBIB NIH HHS R01 EB020644NIBIB NIH HHS U01 EB028235NINDS NIH HHS RF1 NS131063
6 · The paper itself

Abstract

This article examines interdependent design of an optical path and a microelectromechanical system (MEMS) scanning mirror for a miniature, implantable fluorescence microscope with large working distance (WD). Linearized and numerical ray analyses are used to approximately decouple optical and mechanical functions during design. We then maximize scan rate in the scenario of high-NA focusing with a specified WD and field-of-view (FOV). To do so, dynamic rotational analysis is combined with a novel model for expected failure voltage of parametrically-resonant electrostatic MEMS scanning mirrors. Mirrors parameters are set to optimize mirror speed within constraints fixed by optical specifications, while compatible optical path is selected for small objective diameter. A prototype instrument achieving sub-cellular resolution up to approximately

Indexed as

Biomedical optical imagingmechatronic designmicroelectromechanical systems (MEMSs)microsystems

Identifiers

PMID40857484
PMCPMC12355939

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.