Evidence map›Paper›PMID 40857420›Full record

ArticleEvidence-based practice in child and adolescent mental health2025

Practice Experiences for School Reintegration (PrESR): A Pilot Multiphase Optimization Trial of a Virtual Reality Intervention for Adolescents Hospitalized for Suicide-Related Thoughts and Behaviors.

Marisa E Marraccini, Lauren E Delgaty, Telieha J Middleton, Robert Hubal, Leslie A Brick, Anahi Galvan, Eliah Anderson, Madeline Frank, Madeline J Farber, Yixin Li and 4 more

Abstract read
In one paragraph

Article in Evidence-based practice in child and adolescent mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Partnering With Teens With Past Suicide-Related Crises: Development, Application and Refinement of Safety Procedures for Co-Design.Health expectations : an international journal of public participation in health care and health policy · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Marisa E MarracciniSchool of Education, The University of North Carolina at Chapel Hill, Chapel Hill, NC.ORCID 0000-0002-7965-3703
Lauren E DelgatySchool of Education, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
Telieha J MiddletonSchool of Education, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
Robert HubalIntelligent Assessment, Raleigh, NC.ORCID 0000-0003-2637-0918
Leslie A BrickDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI.ORCID 0000-0002-1877-2493
Anahi GalvanSchool of Education, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
Eliah AndersonSchool of Education, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
Madeline FrankSchool of Social Work, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
Madeline J FarberSchool of Education, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
Yixin LiBioMojo, Morrisville, NC.
Jerry HeneghanBioMojo, Morrisville, NC.
David L WyrickSchool of Health and Human Sciences, University of North Carolina at Greensboro, Greensboro, NC.
Dorothy L EspelageSchool of Education, The University of North Carolina at Chapel Hill, Chapel Hill, NC.ORCID 0000-0003-0658-2067
David B GoldstonPsychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC.ORCID 0000-0001-7182-6553

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
North Carolina Translational and Clinical Sciences Institute (NC TraCS)UM1TR004406 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NICHOLAS J SHAHEEN · 2023 to 2026
$37.5M
Practice Experiences for School Reintegration: An Immersive Virtual Reality Program to Enhance Skill Development of Adolescents Hospitalized for Suicidal Thoughts and BehaviorsK23MH122775 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MARRACCINI, MARISA ELLEN · 2020 to 2023
$627k
NCATS NIH HHS UL1 TR002489NCATS NIH HHS UM1 TR004406NIMH NIH HHS K23 MH122775NIMH NIH HHS L30 MH117655
6 · The paper itself

Abstract

Background: Adolescent hospitalization for suicide-related thoughts and behaviors has increased over the past decade, with few interventions shown to improve outcomes post-discharge. Given the majority of adolescents return to school following a suicide-related crisis, we developed and pilot-tested Practice Experiences for School Reintegration (PrESR) Objective: This pilot optimization trial examined the feasibility, acceptability, and safety of PrESR for augmenting standard inpatient care with adolescents hospitalized for suicide-related crises. Method: Using a Multiphase Optimization Strategy (MOST) framework, we recruited adolescents hospitalized for suicide-related thoughts and behaviors ( Results: Research clinicians delivered individual sessions of PrESR with a high degree of fidelity (93-100%), but patients were often discharged before completing more than one skill. Of the participants who participated in the intervention, the majority agreed or strongly agreed with statements endorsing PrESR and its components as important, appropriate, and easy to use, largely supporting acceptability. Participants also provided feedback for improvement, informing slight changes to the next version of the intervention. More generally, PrESR did not appear to result in significant safety concerns based self-reported ratings of subjective distress and pre/post measures of physical symptoms related to cybersickness. Conclusion: Findings support the feasibility of delivering a brief version of PrESR and preliminary acceptability for the intervention. VR technology and content show promising potential for adolescent suicide prevention and mental health support. Future research should examine PrESR for improving patient outcomes and preventing suicide.

Indexed as

AdolescenceCognitive Behavioral TherapyPsychiatric HospitalizationSchool ReintegrationSuicideVirtual Reality

Identifiers

PMID40857420
PMCPMC12288715

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.