ArticleProceedings of the National Academy of Sciences of the United States of America2025
Candidate Denisovan fossils identified through gene regulatory phenotyping.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The global prevalence of horizontal strabismus: A systematic review and meta-analysis with a focus on ethnic variation.Survey of ophthalmologyPooled it
- The gene-regulatory evolution of the human skeleton.Nature · 2026Article
- The Interpupillary Distance Differs Between Ethnicities and Associates with Horizontal Strabismus Patterns: Evidence from a Systematic Review and Meta-Analysis.Clinical ophthalmology (Auckland, N.Z.) · 2026Review
- The interpupillary distance differs between ethnicities and associates with horizontal strabismus patterns: Evidence from a systematic review and meta-analysis.medRxiv : the preprint server for health sciences · 2025Article
- The global prevalence of horizontal strabismus: a systematic review and meta-analysis with a focus on ethnic variation.medRxiv : the preprint server for health sciences · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Denisovans are an extinct group of humans whose morphology is mostly unknown. The scarcity of verified Denisovan fossils makes it challenging to study their anatomy, and how well they were adapted to their environment. We previously developed a genetic phenotyping approach to gain insight into Denisovan anatomy by detecting gene regulatory changes that likely altered Denisovan skeletal morphology. Here, we scan the Middle Pleistocene fossil record for crania matching the predicted Denisovan morphology and might therefore be related to Denisovans. We developed quantitative measures to assess both the proportion and extent of matches. These analyses revealed that the East Asian specimens of
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