Evidence map›Paper›PMID 40856966›Full record

ReviewNano-micro letters2025

Wearable Ultrasound Devices for Therapeutic Applications.

Sicheng Chen, Qunle Ouyang, Xuanbo Miao, Feng Zhang, Zehua Chen, Xiaoyan Qian, Jinwei Xie, Zheng Yan

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nano-micro letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sicheng ChenDepartment of Chemical and Biomedical Engineering, University of Missouri, Columbia, MO, USA.
Qunle OuyangDepartment of Mechanical and Aerospace Engineering, University of Missouri, Columbia, MO, USA.
Xuanbo MiaoDepartment of Mechanical and Aerospace Engineering, University of Missouri, Columbia, MO, USA.
Feng ZhangDepartment of Chemical and Biomedical Engineering, University of Missouri, Columbia, MO, USA.
Zehua ChenDepartment of Chemical and Biomedical Engineering, University of Missouri, Columbia, MO, USA.
Xiaoyan QianDepartment of Chemical and Biomedical Engineering, University of Missouri, Columbia, MO, USA.
Jinwei XieDepartment of Surgery-Transplant and Mary and Dick Holland Regenerative Medicine Program, University of Nebraska Medical Center, Omaha, NE, USA.
Zheng YanDepartment of Chemical and Biomedical Engineering, University of Missouri, Columbia, MO, USA. yanzheng@missouri.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wearable ultrasound devices represent a transformative advancement in therapeutic applications, offering noninvasive, continuous, and targeted treatment for deep tissues. These systems leverage flexible materials (e.g., piezoelectric composites, biodegradable polymers) and conformable designs to enable stable integration with dynamic anatomical surfaces. Key innovations include ultrasound-enhanced drug delivery through cavitation-mediated transdermal penetration, accelerated tissue regeneration via mechanical and electrical stimulation, and precise neuromodulation using focused acoustic waves. Recent developments demonstrate wireless operation, real-time monitoring, and closed-loop therapy, facilitated by energy-efficient transducers and AI-driven adaptive control. Despite progress, challenges persist in material durability, clinical validation, and scalable manufacturing. Future directions highlight the integration of nanomaterials, 3D-printed architectures, and multimodal sensing for personalized medicine. This technology holds significant potential to redefine chronic disease management, postoperative recovery, and neurorehabilitation, bridging the gap between clinical and home-based care.

Indexed as

Closed-loop therapyDrug deliveryNeurorehabilitationTissue regenerationWearable ultrasound devices

Identifiers

PMID40856966
PMCPMC12381330

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.