Evidence map›Paper›PMID 40856859›Full record

ArticleInternational ophthalmology2025

Choriocapillaris perfusion assessed using optical coherence tomography angiography depends on eye color and projection artifact removal.

Dmitrii S Maltsev, Alexey N Kulikov, Anastasiya S Vasyukovich, Yana A Kalinicheva

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Article in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Dmitrii S MaltsevDepartment of Ophthalmology, Military Medical Academy, 21, Botkinskaya str, St. Petersburg, Russia, 194044. glaz.med@yandex.ru.
Alexey N KulikovDepartment of Ophthalmology, Military Medical Academy, 21, Botkinskaya str, St. Petersburg, Russia, 194044.
Anastasiya S VasyukovichDepartment of Ophthalmology, Military Medical Academy, 21, Botkinskaya str, St. Petersburg, Russia, 194044.
Yana A KalinichevaDepartment of Ophthalmology, Military Medical Academy, 21, Botkinskaya str, St. Petersburg, Russia, 194044.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo study variation of choriocapillaris perfusion displayed with optical coherence tomography angiography (OCTA) in dependence of the eye pigmentation.

methodsHealthy individuals and patients with resolved central serous chorioretinopathy (CSCR) with blue or brown eyes were enrolled in this study. Analysis of choriocapillaris flow voids number was performed based on averaged 3 mm OCTA scans with and without projection artifact removal (PAR). The number and total area of flow voids taken every 1000 µm

resultsThirty-six healthy individuals and 28 CSCR patients were included. When PAR was active, brown eyes showed a statistically significant higher number (p < 0.05) and total area (p < 0.05) of large (1000 to 5000 µm

conclusionOCTA displays more flow voids in the choriocapillaris in brown eyes than in blue. This difference results from the activity of PAR.

Indexed as

ArtifactsCentral Serous ChorioretinopathyChoroidFluorescein AngiographyRetinal VesselsTomography, Optical CoherenceAdultCapillariesFemaleFundus OculiHumansMaleMiddle AgedRegional Blood FlowCentral serous chorioretinopathyChoriocapillarisOptical coherence tomography angiographyProjection artifact removalRetinal pigment epithelium

Identifiers

PMID40856859

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.