Evidence map›Paper›PMID 40856435›Full record

ArticleApplied and environmental microbiology2025

Characterization of an isobutylene epoxide hydrolase (IbcK) from the isobutylene-catabolizing bacterium

Nicholas W Faulkner, John B Joyce, Christy Smith, Paul Swartz, Robert B Rose, Eric S Miller, Michael R Hyman

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Hydration and hydrolysis define antibiotic resistance conferred by macrolide esterases.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Aerobic catabolism of isobutylene byApplied and environmental microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nicholas W FaulknerDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, North Carolina, USA.
John B JoyceDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, North Carolina, USA.
Christy SmithDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, North Carolina, USA.
Paul SwartzDepartment of Molecular and Structural Biochemistry, North Carolina State University, Raleigh, North Carolina, USA.
Robert B RoseDepartment of Molecular and Structural Biochemistry, North Carolina State University, Raleigh, North Carolina, USA.
Eric S MillerDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, North Carolina, USA.ORCID 0000-0002-7976-4796
Michael R HymanDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, North Carolina, USA.ORCID 0000-0002-5965-6579

Funding

Resource for Biocomputing Visualization and InformaticsP41GM103311 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2012 to 2017
$8.2M
NC STATE MOLECULAR BIOTECHNOLOGY TRAINING PROGRAM (MBTP)T32GM133366 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Jason M. Haugh, Robert M Kelly · 2020 to 2026
$3.3M
NIGMS NIH HHS P41 GM103311NIGMS NIH HHS T32 GM133366
6 · The paper itself

Abstract

Isobutylene (IB) is produced on a large scale by the petrochemical industry and is metabolized by the aerobic alkene-metabolizing bacterium

Indexed as

AlkenesBacterial ProteinsEpoxide HydrolasesAlkenesBacterial ProteinsEpoxide Hydrolasesisobutylenealkenesbioremediationepoxide hydrolaseisobutyleneisobutylene oxideMTBE

Identifiers

PMID40856435
PMCPMC12442371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.