Evidence map›Paper›PMID 40856282›Full record

ArticlePsychological medicine2025

Cannabis use is associated with changes in psychological and functional well-being during young adulthood: evidence from self-reports and hair analyses.

Lydia Johnson-Ferguson, Michelle Loher, Laura Bechtiger, Clarissa Janousch, Markus R Baumgartner, Tina M Binz, Denis Ribeaud, Manuel Eisner, Boris B Quednow, Lilly Shanahan

Abstract read
In one paragraph

Article in Psychological medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Longitudinal neurocognitive trajectories in a large cohort of youth who use cannabis: combining self-report and toxicology.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lydia Johnson-FergusonJacobs Center for Productive Youth Development, https://ror.org/02crff812University of Zurich, Zurich, Switzerland.ORCID 0000-0003-3717-1332
Michelle LoherJacobs Center for Productive Youth Development, https://ror.org/02crff812University of Zurich, Zurich, Switzerland.ORCID 0000-0002-8669-7683
Laura BechtigerJacobs Center for Productive Youth Development, https://ror.org/02crff812University of Zurich, Zurich, Switzerland.ORCID 0000-0002-7049-2165
Clarissa JanouschJacobs Center for Productive Youth Development, https://ror.org/02crff812University of Zurich, Zurich, Switzerland.ORCID 0000-0002-4160-9758
Markus R BaumgartnerCenter for Forensic Hair Analytics; Zurich Institute of Legal Medicine, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-0979-931X
Tina M BinzCenter for Forensic Hair Analytics; Zurich Institute of Legal Medicine, University of Zurich, Zurich, Switzerland.ORCID 0000-0001-6783-1202
Denis RibeaudJacobs Center for Productive Youth Development, https://ror.org/02crff812University of Zurich, Zurich, Switzerland.ORCID 0000-0002-1668-8319
Manuel EisnerJacobs Center for Productive Youth Development, https://ror.org/02crff812University of Zurich, Zurich, Switzerland.
Boris B QuednowJacobs Center for Productive Youth Development, https://ror.org/02crff812University of Zurich, Zurich, Switzerland.ORCID 0000-0001-7933-2865
Lilly ShanahanJacobs Center for Productive Youth Development, https://ror.org/02crff812University of Zurich, Zurich, Switzerland.ORCID 0000-0002-4534-6924

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 10531C_189008
6 · The paper itself

Abstract

backgroundCannabis use in young adulthood is common, yet few studies have explored how it predicts

methodsData came from a community sample of young adults (

resultsBoth self-reported frequency of cannabis use and hair THC concentrations predicted increases in psychotic-like experiences and internalizing symptoms, increased aggression, decreased general well-being, higher odds of not being in employment, training, or education, and more problematic substance use from age 20 to 24, with small effect sizes. Composite exposure scores derived from self-reports and hair data were not more informative than either source alone.

conclusionsFrequent cannabis use predicted adverse changes in psychopathological outcomes from ages 20 to 24, regardless of how it was assessed.

Indexed as

DronabinolMarijuana UseMental DisordersPsychological Well-BeingCannabisHair AnalysisHumansPsychopathologySelf ReportYoung AdultDronabinolcannabisfunctional well-beinghairpsychopathologyTHCyoung adulthood

Identifiers

PMID40856282
PMCPMC12404324

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.