Evidence map›Paper›PMID 40856026›Full record

ArticleAnnals of coloproctology2025

Transverse perineal support improves long-term outcomes in patients undergoing stapled transanal rectal resection for obstructed defecation syndrome: a multicenter observational case-control study.

Adolfo Renzi, Luigi Marano, Pasquale Talento, Luigi Brusciano, Angela Pezzolla, Domenico Izzo, Carmine Antropoli, Francesco D'Aniello, Giandomenico Di Sarno, Gianluca Minieri and 9 more

Abstract read
In one paragraph

Article in Annals of coloproctology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Article
  4. Beyond stapled transanal rectal resectionWorld journal of gastrointestinal surgery · 2026
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Adolfo RenziDepartment of Surgery, Buonconsiglio Fatebenefratelli Hospital, Naples, Italy.
Luigi MaranoDepartment of Medicine, Academy of Applied Medical and Social Sciences (AMiSNS), Elbląg, Poland.
Pasquale TalentoDepartment of Surgery, Pelvic Floor Center, AUSL-IRCCS Reggio Emilia, Reggio Emilia, Italy.
Luigi BruscianoDepartment of Advanced Medical and Surgical Sciences, University of Campania L. Vanvitelli, Naples, Italy.
Angela PezzollaDepartment of Surgery, University of Bari Aldo Moro, Bari, Italy.
Domenico IzzoDepartment of General and Emergency Surgery, CTO Hospital, AORN dei Colli, Naples, Italy.
Carmine AntropoliDepartment of General Surgery, A. Cardarelli Hospital, Naples, Italy.
Francesco D'AnielloUnit of Surgery, Villa delle Querce Hospital, Naples, Italy.
Giandomenico Di SarnoDepartment of Surgery, Maresca Hospital, Naples, Italy.
Gianluca MinieriDepartment of Surgery, Buonconsiglio Fatebenefratelli Hospital, Naples, Italy.
Grazia CantoreDepartment of Surgery, Buonconsiglio Fatebenefratelli Hospital, Naples, Italy.
Gianmattia TerraccianoDepartment of Surgery, Buonconsiglio Fatebenefratelli Hospital, Naples, Italy.
Domenico BarbatoDepartment of Surgery, Buonconsiglio Fatebenefratelli Hospital, Naples, Italy.
Ludovico DocimoDepartment of Advanced Medical and Surgical Sciences, University of Campania L. Vanvitelli, Naples, Italy.
Massimo AntropoliDepartment of General Surgery, A. Cardarelli Hospital, Naples, Italy.
Alessio PalumboDepartment of General Surgery, A. Cardarelli Hospital, Naples, Italy.
Michele LanzaDepartment of General Surgery, A. Cardarelli Hospital, Naples, Italy.
Emanuele Mario CaputiDepartment of General Surgery, A. Cardarelli Hospital, Naples, Italy.
Antonio BrillantinoDepartment of General Surgery, A. Cardarelli Hospital, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the safety and long-term efficacy of stapled transanal rectal resection (STARR) combined with the transverse perineal support (TPS) procedure in the surgical treatment of obstructed defecation syndrome (ODS) associated with internal rectal prolapse and excessive perineal descent (PD).

methodsThis multicenter observational case-control study involved 7 European centers. During the initial study period, patients underwent STARR alone (group 1), while in the subsequent period, patients received STARR combined with TPS (group 2). All patients were followed clinically at 6, 12, 36, and 60 months, and were offered radiological evaluation between 3 and 5 years postoperatively.

resultsThe median postoperative ODS score was similar between groups at 6 months (6 [range, 2-15] vs. 5 [range, 2-13]; P=0.16, Mann-Whitney U-test), but at 36 months, it was significantly lower in group 2 compared to group 1 (11 [range, 5-16] vs. 5 [range, 2-15]; P<0.001, Mann-Whitney U-test), with stable results maintained through 5 years. The success rate followed a similar trend. Postoperative maximum PD during straining remained unchanged in group 1, whereas it significantly decreased compared to preoperative values in group 2.

conclusionsThe addition of TPS to STARR in the surgical treatment of ODS associated with internal rectal prolapse and excessive PD appears to significantly improve long-term success rates and correct descending perineum.

Indexed as

Obstructed defecation syndromePerineal descentRectal prolpaseRectoceleTrasverse perineal support

Identifiers

PMID40856026
PMCPMC12399314

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.