Evidence map›Paper›PMID 40855895›Full record

ArticleJU open plus2025

Population-Specific Radiomics From Biparametric Magnetic Resonance Imaging Improves Prostate Cancer Risk Stratification in African American Men.

Abhishek Midya, Sreeharsha Tirumani, Leonardo Kayat Bittencourt, Sena Azamat, Siddharth Balakrishnan, Amogh Hiremath, Sarah Wido, Pingfu Fu, Lee Ponsky, Anant Madabhushi and 1 more

Abstract read
In one paragraph

Article in JU open plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Abhishek MidyaEmory University and Georgia Institute of Technology, Atlanta, Georgia.ORCID 0000-0003-2149-7098
Sreeharsha TirumaniUniversity Hospitals Cleveland Medical Center, Cleveland, Ohio.ORCID 0000-0002-5288-8916
Leonardo Kayat BittencourtUniversity Hospitals Cleveland Medical Center, Cleveland, Ohio.ORCID 0000-0001-9175-9626
Sena AzamatEmory University and Georgia Institute of Technology, Atlanta, Georgia.
Siddharth BalakrishnanCase Western Reserve University, Cleveland, Ohio.
Amogh HiremathCase Western Reserve University, Cleveland, Ohio.ORCID 0000-0001-6937-9141
Sarah WidoUniversity Hospitals Cleveland Medical Center, Cleveland, Ohio.
Pingfu FuCase Western Reserve University, Cleveland, Ohio.ORCID 0000-0002-2334-5218
Lee PonskyUniversity Hospitals Cleveland Medical Center, Cleveland, Ohio.
Anant MadabhushiEmory University and Georgia Institute of Technology, Atlanta, Georgia.ORCID 0000-0002-5741-0399
Rakesh ShiradkarIndiana University, Indianapolis, Indiana.ORCID 0000-0003-2852-3869

Funding

Pathology CoreU54CA254566 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI MADABHUSHI, ANANT · 2020 to 2024
$5.0M
Oral Cavity Quantitative Histomorphometric Risk Classifier (OHbIC) in Oral Cavity Squamous Cell Carcinoma (OC-SCC)R01CA249992 · NCI · EMORY UNIVERSITY · PI LEWIS, JAMES, MADABHUSHI, ANANT · 2021 to 2025
$3.2M
Computerized histologic image predictor of cancer outcomeR01CA202752 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI FELDMAN, MICHAEL D, GANESAN, SHRIDAR · 2016 to 2020
$3.1M
Quantitative Histomorphometric Risk Classifier (QuHbIC) in HPV + Oropharyngeal CarcinomaR01CA220581 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI KOYFMAN, SHLOMO, LEWIS, JAMES · 2018 to 2023
$3.1M
Computerized Histologic Risk Predictor (CHiRP) for Early Stage Lung CancersR01CA216579 · NCI · EMORY UNIVERSITY · PI FU, PINGFU, LLOYD, MARK · 2018 to 2023
$3.1M
Prognostic and Predictive Digital Tissue Image Assay for Prostate CancerR01CA268287 · NCI · EMORY UNIVERSITY · PI GUPTA, SHILPA, LAL, PRITI · 2022 to 2025
$3.0M
MR Fingerprinting and Computerized Decision Support for Prostate CancerR01CA208236 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GULANI, VIKAS, PONSKY, LEE EVAN · 2017 to 2022
$3.0M
Novel Radiomics for Predicting Response to Immunotherapy for Lung CancerR01CA257612 · NCI · EMORY UNIVERSITY · PI Anant Madabhushi, Vamsidhar Velcheti · 2021 to 2026
$2.7M
An AI-enabled Digital Pathology Platform for Multi-Cancer Diagnosis, Prognosis and Prediction of Therapeutic BenefitU01CA269181 · NCI · EMORY UNIVERSITY · PI Anant Madabhushi, tanuja shet · 2022 to 2026
$2.5M
RadxTools for assessing tumor treatment response on imagingU01CA248226 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI TIWARI, PALLAVI, VISWANATH, SATISH EASWAR · 2020 to 2022
$1.4M
HistoTools: A suite of digital pathology tools for quality control, annotation and dataset identificationU01CA239055 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI JANOWCZYK, ANDREW ROBERT, MADABHUSHI, ANANT · 2019 to 2022
$1.0M
A Study to Validate and Improve an Automated Image Analysis Algorithm to Detect Tuberculosis in Sputum Smear SlidesR43EB028736 · NIBIB · DIASCOPIC, LLC · PI MADABHUSHI, ANANT, SERIF, CARY · 2019 to 2019
$225k
BLRD VA I01 BX004121BLRD VA IK6 BX006185NCI NIH HHS R01 CA202752NCI NIH HHS R01 CA208236NCI NIH HHS R01 CA216579NCI NIH HHS R01 CA220581NCI NIH HHS R01 CA249992NCI NIH HHS R01 CA257612NCI NIH HHS R01 CA268287NCI NIH HHS U01 CA239055NCI NIH HHS U01 CA248226NCI NIH HHS U01 CA269181NCI NIH HHS U54 CA254566NIBIB NIH HHS R43 EB028736
6 · The paper itself

Abstract

Purpose: To quantify population-specific differences in prostate cancer (PCa) presentation between African American (AA) and White (W) men on MRI using radiomics. Materials and Methods: We identified N = 149 men with PCa who underwent 3T MRI, a confirmatory biopsy and for whom self-reported race was available. Patient studies were partitioned into training (D Results: Radiomic features from PCa ROIs on biparametric MRI associated with csPCa were observed to be different in AA compared with W men, especially in the peritumoral region. Population-specific radiomic models outperformed similarly trained C Conclusions: Accounting for population-specific differences in radiomics may enable improved PCa risk stratification at MRI among AA men compared with a population agnostic approach.

Indexed as

African AmericandisparitiesMRIprostate cancerradiomics

Identifiers

PMID40855895
PMCPMC12377208

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.