Evidence map›Paper›PMID 40855812›Full record

ArticleJournal of research on adolescence : the official journal of the Society for Research on Adolescence2025

Mental health and substance use problems among adolescents in Lesotho: Prevalence, access to care, and association with lifestyle factors.

Natalie E Johnson, Irene Falgas-Bague, Frédérique Chammartin, Felix Gerber, Tristan T Lee, Ravi Gupta, Relebohile Mjadu, Jonase Nthunya, Moleboheng Mokebe, Retsélisitsoe Makabateng and 5 more

Abstract read
In one paragraph

Article in Journal of research on adolescence : the official journal of the Society for Research on Adolescence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Mental health and substance use problems among adolescents in Lesotho: Prevalence, access to care, and association with lifestyle factors.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Natalie E JohnsonDivision of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.ORCID 0000-0001-8379-1183
Irene Falgas-BagueDivision of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.ORCID 0000-0002-1072-4243
Frédérique ChammartinDivision of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.
Felix GerberDivision of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.ORCID 0000-0002-9736-1907
Tristan T LeeDivision of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.
Ravi GuptaSolidarMed, Maseru, Lesotho.
Relebohile MjaduSolidarMed, Maseru, Lesotho.
Jonase NthunyaSolidarMed, Maseru, Lesotho.
Moleboheng MokebeSolidarMed, Maseru, Lesotho.
Retsélisitsoe MakabatengSolidarMed, Maseru, Lesotho.
Mamoronts'ane P SematleSolidarMed, Maseru, Lesotho.
Pearl LetsoelaGovernment of Lesotho Ministry of Health and Social Welfare, Maseru, Lesotho.
Niklaus D LabhardtDivision of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.ORCID 0000-0003-3599-1791
Alain AmstutzDivision of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.ORCID 0000-0003-1716-993X
Jennifer M BelusDivision of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.

Funding

Swiss Agency for Development and Cooperation 7F-10345.01.01Swiss National Science Foundation P500PM_221961Swiss National Science Foundation PCEFP3_181355Swiss National Science Foundation PZ00P1_201690World Diabetes Foundation WDF-1778
6 · The paper itself

Abstract

Adolescence is a developmental window in which mental health symptomatology and other health behaviors can set lifelong trajectories. Yet, adolescent development research in rural areas of low-resource communities is severely lacking. Conceptualized in the Adolescent Well-Being Framework, where diet and activity form a core domain of well-being, we examined two modifiable risk behaviors (sugar-sweetened beverage consumption and physical activity) and their associations with mental health and substance use problems among 1351 adolescents aged 10-17 years (51% girls) in a rural setting in Lesotho, southern Africa. Standardized screening measures showed at least one clinically relevant mental health problem among 3% of the overall sample and 5% among 15-17 year-olds. Among those in the overall sample meeting these criteria, 45% recognized a need for help, yet only 17% obtained any care, leaving an 83% treatment gap. After adjusting for age and sex, any sugar-sweetened beverage consumption was associated with having at least one mental health symptom or recent substance use and with clinically relevant mental health and substance use problems. Physical activity showed no significant associations. Although the overall prevalence of clinically relevant mental health and substance use problems was relatively low, low levels of problem awareness suggest a need for adolescent-appropriate demand-side interventions for early treatment. Future research may explore possible indigenous protective factors underlying the low prevalence and clarify the pathway between health behaviors and mental health problems.

Indexed as

Mental DisordersAdolescentChildCross-Sectional StudiesExerciseFemaleHealth Services AccessibilityHumansLesothoMaleMental HealthPrevalenceSubstance-Related DisordersSugar-Sweetened BeveragesadolescentsanxietydepressionPTSDsubstance usesugar‐sweetened beverages

Identifiers

PMID40855812
PMCPMC12379077

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.