Evidence map›Paper›PMID 40855671›Full record

Observational studyCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2025

Prevalence and Prognostic Impact of Coronary Chronic Total Occlusions in Patients With Cardiogenic Shock.

Michael Behnes, Moritz Schmidberger, Giuseppe Vadalà, Alice Moroni, Juan-Luis Guiterrez-Chico, Stylianos Pyxaras, Alexander Bufe, Florian Krötz, Kambis Mashayekhi, Mohamed Ayoub and 6 more

Abstract readObservational Study
In one paragraph

Observational study in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Michael BehnesDepartment of Cardiology, Angiology, Haemostaseology and Medical Intensive Care, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Baden-Württemberg, Germany.ORCID 0000-0001-5970-0093
Moritz SchmidbergerDepartment of Cardiology, Angiology, Haemostaseology and Medical Intensive Care, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Baden-Württemberg, Germany.
Giuseppe VadalàDivision of Cardiology, University Hospital "P. Giaccone", Palermo, Italy.ORCID 0000-0003-0869-4855
Alice MoroniDivision of Cardiology, Imelda Hospital, Bonheiden, Belgium.ORCID 0000-0003-0160-7317
Juan-Luis Guiterrez-ChicoBundeswehrzentralkrankenhaus, Koblenz, Germany.
Stylianos PyxarasDepartment of Cardiology, Klinikum Fürth, Fürth, Germany.
Alexander BufeInterventional Cardiology, HELIOS Klinikum Wuppertal, Herzzentrum, Universität Witten/Herdecke, Herdecke, Germany.
Florian KrötzDepartment of Cardiology, Klinikum Starnberg, Starnberg, Germany.
Kambis MashayekhiDepartment of Internal Medicine and Cardiology, Mediclin Heart Centre Lahr, Lahr, Germany.ORCID 0000-0001-8119-8941
Mohamed AyoubDivision of Cardiology and Angiology, Heart Center University of Bochum-Bad Oeynhausen, Bad Oeynhausen, Germany.
Jonas RusnakDepartment of Cardiology, Angiology, Haemostaseology and Medical Intensive Care, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Baden-Württemberg, Germany.
Mohammad AbumayyalehDepartment of Cardiology, Angiology, Haemostaseology and Medical Intensive Care, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Baden-Württemberg, Germany.
Jonas DuddaDepartment of Cardiology, Angiology, Haemostaseology and Medical Intensive Care, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Baden-Württemberg, Germany.
Kathrin WeidnerDepartment of Cardiology, Angiology, Haemostaseology and Medical Intensive Care, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Baden-Württemberg, Germany.
Ibrahim AkinDepartment of Cardiology, Angiology, Haemostaseology and Medical Intensive Care, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Baden-Württemberg, Germany.ORCID 0000-0003-1974-6147
Tobias SchuppDepartment of Cardiology, Angiology, Haemostaseology and Medical Intensive Care, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Baden-Württemberg, Germany.ORCID 0000-0001-8171-7617

Funding

The authors received no specific funding for this work.
6 · The paper itself

Abstract

backgroundMortality in patients with cardiogenic shock (CS) remains high despite advanced treatment strategies in CS patients, underlining the need for the identification of predictors of prognosis in CS patients. Therefore, the present study investigates the prognostic impact of coronary chronic total occlusions (CTO) in patients with CS.

methodsAll consecutive patients being acutely admitted with CS to an intensive care unit (ICU) and undergoing invasive coronary angiography (ICA) from 2019 to 2021 were included, irrespective of the etiology of CS. Patients with at least one CTO were compared to non-CTO patients with regard to the risk of all-cause mortality at 30 days. Further risk stratification was performed according to the extent of coronary artery disease (CAD).

resultsA total of 192 CS patients undergoing ICA during index hospitalization were included. At least one CTO was present in 24% of CS patients. Patients with CTO were older (median 78 vs. 68; p = 0.001) and presented more frequently with non-ST-elevated myocardial infarction (21% vs. 12%; p = 0.048). The presence of a CTO was associated with higher rates of 30-days all-cause mortality (70.2% vs. 47.6%; HR = 1.783, 95% CI 1.176-2.702; p = 0.009), even after multivariable adjustment (adjusted HR = 1.898; 95% CI 1.116-3.229; p = 0.018). Patients with CTO were accompanied by an even higher 30-days all-cause mortality as compared to patients with multi-vessel CAD without CTO (adjusted HR = 1.723; 95% CI 1.058-2.805; p = 0.029).

conclusionCoronary CTO are common in patients with CS and represent an independent predictor of all-cause mortality at 30 days.

Indexed as

Coronary OcclusionShock, CardiogenicAgedAged, 80 and overChronic DiseaseCoronary AngiographyFemaleHumansMaleMiddle AgedPrevalencePrognosisRetrospective StudiesRisk AssessmentRisk FactorsTime Factorscardiogenic shockchronic total occlusioncoronary artery diseasecritical careinternal medicine

Identifiers

PMID40855671
PMCPMC12584578

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.