Observational studyAnnals of medicine2025
Comparison of sequential cryoprobe and biopsy forceps in endobronchial ultrasound-guided transbronchial needle aspiration for mediastinal and hilar lesions: a prospective observational study.
Observational study in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- A multimodal bronchoscopic approach for diagnosing peripheral ground-glass nodules using Cone-Beam computed tomography and cryobiopsy: a preliminary study.Annals of medicine · 2026Article
- Diagnostic value of EBUS-guided transbronchial mediastinal cryobiopsyERJ open research · 2026Article
- A novel technique using diode laser-assisted endobronchial ultrasound-guided transbronchial biopsy: a brief report.Journal of thoracic disease · 2026Article
- Annual progress in transbronchial diagnosis and treatment of pulmonary malignant tumors [2025]: a narrative review.Translational lung cancer research · 2026Review
- Bronchoscopic cryotherapy for biopsy and debulking of tracheal myxosarcoma in a cat.JFMS open reportsArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a safe and widely used technique for diagnosing mediastinal/hilar lesions. Recent studies showed that combining EBUS-TBNA with cryobiopsy (EBUS-transbronchial mediastinal cryobiopsy, EBUS-TMC) or forceps biopsy (EBUS-intranodal forceps biopsy, EBUS-IFB) enhances diagnostic accuracy by obtaining larger tissue samples. However, limited data is comparing the efficacy of EBUS-TMC and EBUS-IFB. This study aims to assess the effectiveness of these biopsy techniques in diagnosing mediastinal and hilar lesions.
methodsPatients with mediastinal/hilar lesions who underwent EBUS-TBNA and mediastinal biopsy from November 2022 to March 2024 were enrolled. Following needle aspiration, cryobiopsy and forceps biopsies were performed. The primary endpoint was diagnostic accuracy.
resultsA total of 219 mediastinal/hilar lesions were evaluated in 183 patients. EBUS-TMC demonstrated higher diagnostic accuracy than EBUS-IFB (95.4% vs. 84.9%,
conclusionsEBUS-TMC is an effective diagnostic and auxiliary method for mediastinal/hilar lesions, enhancing yield rates and tissue acquisition.
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