Evidence map›Paper›PMID 40855572›Full record

ArticleEuropean journal of medical research2025

Characteristics of obstructive sleep apnea in children with cerebral palsy: a comparative study with healthy children.

Yangyang Cao, Yanyan Sun, Junhui Wang, Juan Song, Qianyu Guo, Xirui Peng, Bingbing Li, Bibo Liu, Dengna Zhu, Yiran Xu and 2 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yangyang CaoHenan Key Laboratory of Child Brain Injury and Henan Pediatric Clinical Research Center, Department of Pediatrics, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, People's Republic of China.
Yanyan SunDepartment of Human Anatomy, School of Basic Medicine, Zhengzhou University, Zhengzhou, Henan, 450052, People's Republic of China.
Junhui WangHenan Key Laboratory of Child Brain Injury and Henan Pediatric Clinical Research Center, Department of Pediatrics, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, People's Republic of China.
Juan SongHenan Key Laboratory of Child Brain Injury and Henan Pediatric Clinical Research Center, Department of Pediatrics, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, People's Republic of China.
Qianyu GuoHenan Key Laboratory of Child Brain Injury and Henan Pediatric Clinical Research Center, Department of Pediatrics, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, People's Republic of China.
Xirui PengHenan Key Laboratory of Child Brain Injury and Henan Pediatric Clinical Research Center, Department of Pediatrics, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, People's Republic of China.
Bingbing LiHenan Key Laboratory of Child Brain Injury and Henan Pediatric Clinical Research Center, Department of Pediatrics, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, People's Republic of China.
Bibo LiuHenan Key Laboratory of Child Brain Injury and Henan Pediatric Clinical Research Center, Department of Pediatrics, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, People's Republic of China.
Dengna ZhuHenan Key Laboratory of Child Brain Injury and Henan Pediatric Clinical Research Center, Department of Pediatrics, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, People's Republic of China.
Yiran XuHenan Key Laboratory of Child Brain Injury and Henan Pediatric Clinical Research Center, Department of Pediatrics, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, People's Republic of China.
Changlian ZhuHenan Key Laboratory of Child Brain Injury and Henan Pediatric Clinical Research Center, Department of Pediatrics, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, People's Republic of China.
Jun WangHenan Key Laboratory of Child Brain Injury and Henan Pediatric Clinical Research Center, Department of Pediatrics, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, People's Republic of China. wj3028@163.com.

Funding

Henan Provincial Department of Science and Technology key research and development and promotion special project grant NO. 202102310359The National Key Research and Development Program from the Ministry of Science and Technology of the People's Republic of China grant NO. 2022YFC2704800The National Natural Science Foundation of China grant NO. U21A20347
6 · The paper itself

Abstract

backgroundObstructive sleep apnea (OSA) can affect the growth and development of children, and serious OSA can lead to significant complications if left untreated. Children with cerebral palsy (CP) also experience sleep problems. Therefore, the present study examined the prevalence and differences of OSA in children with CP compared to healthy children. In addition, it sought to classify the children with CP according to different severities and clinical types in order to investigate whether there are differences in the severity of OSA and in sleep and respiratory characteristics among groups of children with different severities of CP.

methodsOne hundred and fifty-six children with CP and one hundred and fifty healthy children completed the Pediatric Sleep Questionnaire (PSQ). Based on the PSQ results, a threshold of 0.33 was used to define high risk of OSA. Children identified as high risk underwent polysomnography (PSG) to analyze their sleep structure, breathing events, oxygen saturation, and heart rate.

results48.7% of children with CP and 26.67% of healthy children identified as high risk of OSA. The prevalence of OSA in children with CP (23.72%) was higher than that in healthy children (7.3%). Thus, children with CP have both a higher risk and a higher prevalence of OSA than healthy children, but the difference in the severity of OSA was not statistically significant.Also, there were no differences in OSA severity among groups of children with varying severities and types of CP. The proportion of rapid eyes movement (REM) sleep time, minimum transcutaneous oxygen saturation (SpO

conclusionChildren with CP have a higher risk and prevalence of OSA than healthy children. Although there were no differences in OSA severity among groups of children with varying severities of CP, children with severe CP exhibited more severe sleep disturbances and breathing issues compared to children with mild and moderate CP.

Indexed as

Cerebral PalsySleep Apnea, ObstructiveCase-Control StudiesChildChild, PreschoolFemaleHumansMalePolysomnographyPrevalenceSeverity of Illness IndexSurveys and QuestionnairesCerebral palsyObstructive sleep apneaPediatric sleep questionnairePolysomnography

Identifiers

PMID40855572
PMCPMC12379394

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.