SynthesisBMC anesthesiology2025
Efficacy of anterior quadratus lumborum block at the lateral supra-arcuate ligament for pain control in abdominal surgery: a systematic review and meta-analysis.
Synthesis in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Efficacy of Liposomal Bupivacaine for Anterior Quadratus Lumborum Block in Laparoscopic Gynecological Surgery: A Randomized Controlled Trial.Drug design, development and therapy · 2026Trial
- Anterior Quadratus Lumborum Block: A Scoping Review of Anatomical Rationale, Techniques, and Clinical Applications.Pain and therapy · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA critical component of postoperative abdominal surgery recovery is the efficacy of analgesia administered postsurgery. In 2020, a novel approach to the quadratus lumborum block (QLB) was proposed: anterior quadratus lumborum block at the lateral supra-arcuate ligament (QLB-LSAL). A hypothesis indicating that the performance of the block would provide superior analgesia for abdominal surgery was developed. The primary aim of this meta-analysis was to assess the efficacy of the QLB-LSAL in reducing postoperative opioid use. The secondary objective was to assess the effects of this block on postoperative pain-related indicators, including pain scores, time to first patient-controlled analgesia (PCA) activation, and the occurrence of postoperative nausea and vomiting (PONV).
methodsA comprehensive search of relevant databases, including PubMed, the Cochrane Library, EMBASE, Web of Science, and other relevant sources, was conducted. Studies were screened for broad eligibility by title and abstract, followed by full-text screening. Data were extracted from the included studies and then analyzed via Review Manager software (version 5.4) and STATA (version 18.0 MP-Parallel Edition).
resultsA total of eight studies involving 596 participants were included in the analysis. The QLB-LSAL group demonstrated a statistically significant reduction in postoperative opioid consumption within the first 24 h (mean difference [MD] = - 10.88, 95% confidence interval [CI]: - 12.37 to - 9.39, P < 0.00001, I
conclusionsThe anterior quadratus lumborum block at the lateral supra-arcuate ligament significantly provides less 24-h postoperative opioid consumption after abdominal surgery, prolongs the time to first patient-controlled analgesia activation, and lowers the incidence of postoperative nausea and vomiting.
trial registrationThe protocol of this study was registered with PROSPERO (Registration Number: CRD42024614871).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.