Evidence map›Paper›PMID 40855476›Full record

ArticleColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2025

Effectiveness of transanal irrigation in low anterior resection syndrome.

Shreya Jauhari, Digby Hopkinson-Woolley, Karen Curran, Rebecca Doyle, Helen Boffin, Kim Gorissen, Sandeep Singh

Abstract read
In one paragraph

Article in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Effectiveness of transanal irrigation in low anterior resection syndrome.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shreya JauhariOxford University Hospitals Trust, Oxford, UK.ORCID https://orcid.org/0000-0002-8885-403X
Digby Hopkinson-WoolleyOxford University Hospitals Trust, Oxford, UK.
Karen CurranOxford University Hospitals Trust, Oxford, UK.
Rebecca DoyleOxford University Hospitals Trust, Oxford, UK.
Helen BoffinOxford University Hospitals Trust, Oxford, UK.
Kim GorissenOxford University Hospitals Trust, Oxford, UK.ORCID https://orcid.org/0000-0001-7214-1222
Sandeep SinghOxford University Hospitals Trust, Oxford, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLow anterior resection syndrome (LARS) is a frequent issue leading to bowel dysfunction after anterior resection surgery. NICE guidelines state that there is limited research around the management of LARS. Transanal irrigation (TAI) is a suggested treatment by guidelines; however, there is limited research surrounding the effectiveness of this treatment.

aimThe aim of this prospective study was to evaluate the effectiveness of TAI in reducing LARS score post anterior resection surgery.

methodsPatients who were referred to the pelvic floor nurse specialist team between 2019 and 2023 with bowel dysfunction post anterior resection surgery were evaluated. Bowel dysfunction was assessed using the LARS scoring system during the first assessment and on discharge. These patients were offered TAI and trained to perform TAI. Patients with missing LARS scores and those who were not using TAI were excluded from the study.

resultsOf the total 37 patients who were referred and using TAI, 16 were excluded. In total, 21 patients were included (12 male, 9 female). At baseline, 33% of patients were recorded to have minor LARS, and 66% with major LARS. At discharge, there was a significant improvement in LARS score (80% of patients reported no LARS, 10% minor LARS and 10% major LARS). Overall, the LARS score at discharge was significantly lower among patients who underwent irrigation (mean 34.57 vs. 12.48, p = 0.0000000038).

conclusionOur study shows the importance of TAI in the management of bowel dysfunction post anterior resection for rectal cancer, with more than two-third of patients' symptom improvement.

Indexed as

Postoperative ComplicationsProctectomyTherapeutic IrrigationAdultAgedAnal CanalFemaleHumansLow Anterior Resection SyndromeMaleMiddle AgedProspective StudiesRectal NeoplasmsSyndromeTreatment Outcomebowel dysfunctionfunctional outcomesLARS scorelow anterior resection syndrome (LARS)pelvic floor rehabilitationrectal cancertransanal irrigation (TAI)

Identifiers

PMID40855476
PMCPMC12379037

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.