Evidence map›Paper›PMID 40855467›Full record

ArticleBMC infectious diseases2025

Human herpesvirus type 4 combined with Brucella abortus meningitis case report.

Jingjing Yang, Feixiang Zhang, Xiaolong Guo, Jiahui Liu

Abstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Jingjing Yang *Affiliated Baotou Clinical College of Inner Mongolia Medical University, Baotou, Inner Mongolia, 014000, China.
Feixiang Zhang *Baotou City Central Hospital, Baotou , Inner Mongolia, 014000, China.
Xiaolong Guo *Baotou City Central Hospital, Baotou , Inner Mongolia, 014000, China.
Jiahui LiuDepartment of Neurology, Baotou City Central Hospital, Baotou, Inner Mongolia, 014000, China. 15598336885@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo observe and analyse the clinical characteristics, diagnosis and treatment of Human herpesvirus type 4 combined with Brucella abortus meningitis, in order to improve clinicians' understanding of this disease.

methodsThe clinical data of a patient withHuman herpesvirus type 4 combined with Brucella abortus meningitis diagnosed on 8 January 2024 in Baotou People's Hospital were analysed. Results The case was a middle-aged female patient with the main symptoms of dizziness and numbness and weakness of the limbs. The pathogenic microorganisms were detected as macrogenomic and copy number anomalies by double-homology: Human herpesvirus type 4 was detected as sequence number 13, and the serum Brucella abortus tiger-red plate agglutination test was positive.

resultsBrucella tube agglutination test: 1:400 ++. Symptoms improved significantly after treatment with doxycycline + rifampicin + cotrimoxazole tablets and prednisone acetate tablets.

conclusionHuman herpesvirus type 4 (EBV) combined with Brucella abortus meningitis is a rare infectious encephalitis with a poor prognosis and high recurrence rate. A step therapy strategy of antibiotics combined with glucocorticoids is currently recommended to control acute phase symptoms and reduce the risk of recurrence.

Indexed as

Brucella abortusBrucellosisEpstein-Barr Virus InfectionsHerpesvirus 4, HumanMeningitis, BacterialAnti-Bacterial AgentsFemaleHumansMiddle AgedAnti-Bacterial AgentsBrucella meningitisHHV-4Macrogenome second-generation sequencing (mNGS)

Identifiers

PMID40855467
PMCPMC12376623

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