Evidence map›Paper›PMID 40855319›Full record

ArticleCritical care (London, England)2025

Tipping the balance: early post-resuscitation fluid accumulation and outcome after cardiac arrest.

Chiara Crivellari, Aurora Magliocca, Cristina Dulama, Giulia Merigo, Fabiana Madotto, Mauro Panigada, Giacomo Grasselli, Giuseppe Ristagno

Abstract readLetter
In one paragraph

Article in Critical care (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chiara CrivellariSchool of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy.
Aurora MaglioccaDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
Cristina DulamaDepartment of Anesthesiology, Intensive Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Giulia MerigoDepartment of Anesthesiology, Intensive Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Fabiana MadottoDepartment of Anesthesiology, Intensive Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Mauro PanigadaDepartment of Anesthesiology, Intensive Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Giacomo GrasselliDepartment of Anesthesiology, Intensive Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Giuseppe RistagnoDepartment of Anesthesiology, Intensive Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. gristag@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a cohort of 109 adults resuscitated from out-of-hospital cardiac arrest and admitted to a tertiary intensive care unit (ICU), non-survivors showed higher mean fluid intake, reduced urine output, and greater cumulative positive fluid balance during the first 96 h after resuscitation. Daily increases in mean fluid balance were independently associated with ICU mortality after adjustment for confounding factors. These observations suggest that sustained positive fluid balance is linked to adverse outcomes, underscoring the potential value of more individualized or restrictive fluid management following cardiac arrest.

Indexed as

Cardiopulmonary ResuscitationFluid TherapyHeart ArrestOut-of-Hospital Cardiac ArrestWater-Electrolyte BalanceAgedCohort StudiesFemaleHumansIntensive Care UnitsMaleMiddle AgedTreatment Outcome

Identifiers

PMID40855319
PMCPMC12376454

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.