Trial reportBMC anesthesiology2025
Effect of propofol sedation via a narrow-bore tube on hypoxemia risk during gastroscopy: a single-center, prospective, randomized controlled trial.
Trial report in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- An Oxycodone-Based Conscious Analgesia Strategy with Supplemental Low-Dose Propofol Improves Safety in Elderly Obese Patients Undergoing Gastroscopy: A Prospective Randomized Controlled Trial.Drug design, development and therapy · 2026Trial
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHypoxemia is a common adverse event during propofol sedation for gastrointestinal endoscopy. Maintaining a sufficiently slow infusion rate is known to reduce respiratory depression caused by propofol, but achieving this consistently is challenging due to variations in manual techniques. This study evaluated the use of a narrow-bore extension tube to administer propofol, which passively slows infusion, to reduce hypoxemia during gastroscopy sedation.
methodsA randomized controlled trial was conducted among patients undergoing propofol sedation for gastroscopy. Participants were assigned to either the narrow-bore extension tube group, which restricts infusion rates, or the control group receiving a standard-bore extension tube with unrestricted infusion rates. The primary outcome was the incidence of hypoxemia (SpO
resultsThe incidence of hypoxemia was significantly lower in the narrow-bore extension tube (11.7% vs. 27.0%, p = 0.001), and there was a corresponding decrease in severe hypoxemia (7.3% vs. 19.7%, p = 0.003). The median time to achieve deep sedation was longer in the narrow-bore group (70 vs. 54 s; p < 0.001). The greatest reduction in hypoxemia was observed in overweight patients (BMI 25-28 kg/m
conclusionsUsing a narrow-bore extension tube to control propofol infusion rates significantly reduces hypoxemia during gastroscopy sedation. This cost-effective strategy is especially beneficial for higher-risk patients, such as those who are overweight.
trial registrationThe clinical trial was registered on Chinese Clinical Trial Register on December 16, 2024 (ChiCTR2400094042).
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