Evidence map›Paper›PMID 40855242›Full record

ArticleNature plants2025

Apoplastic metabolomics reveals sugars as mesophyll messengers regulating guard cell ion transport under red light.

Yotam Zait, Mengmeng Zhu, Eigo Ando, Yunqing Zhou, Adi Yaaran, Sunheng Yon, Mami Okamoto, Yuki Hayashi, Masami Y Hirai, Timothy Jegla and 3 more

Abstract read
In one paragraph

Article in Nature plants, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yotam Zait *Department of Biology, Penn State University, University Park, PA, USA.
Mengmeng Zhu *Department of Biology, Penn State University, University Park, PA, USA.
Eigo Ando *Graduate School of Science and Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Furo-cho, Chikusa, Nagoya, Aichi, Japan.ORCID 0000-0001-6232-6573
Yunqing ZhouDepartment of Biology, Penn State University, University Park, PA, USA.ORCID 0000-0002-2808-4192
Adi YaaranThe Robert H. Smith Institute of Plant Sciences and Genetics in Agriculture, Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel.
Sunheng YonThe Robert H. Smith Institute of Plant Sciences and Genetics in Agriculture, Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel.
Mami OkamotoRIKEN Center for Sustainable Resource Science, Yokohama, Kanagawa, Japan.
Yuki HayashiGraduate School of Science and Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Furo-cho, Chikusa, Nagoya, Aichi, Japan.
Masami Y HiraiRIKEN Center for Sustainable Resource Science, Yokohama, Kanagawa, Japan.ORCID 0000-0003-0802-6208
Timothy JeglaDepartment of Biology, Penn State University, University Park, PA, USA.
Toshinori KinoshitaGraduate School of Science and Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Furo-cho, Chikusa, Nagoya, Aichi, Japan. kinoshita@bio.nagoya-u.ac.jp.ORCID 0000-0001-7621-1259
Sixue ChenDepartment of Biology, University of Mississippi, Oxford, MS, USA. schen8@olemiss.edu.ORCID 0000-0002-6690-7612
Sarah M AssmannDepartment of Biology, Penn State University, University Park, PA, USA. sma3@psu.edu.ORCID 0000-0003-4541-1594

Funding

West Coast Metabolomics Center for Compound IdentificationU2CES030158 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI FIEHN, OLIVER · 2018 to 2021
$4.1M
Israel Science Foundation (ISF) 2076/23MEXT | Japan Society for the Promotion of Science (JSPS) 20H05687, 20H05910, 25H00989, 25H01346MEXT | Japan Society for the Promotion of Science (JSPS) 20J00392NIEHS NIH HHS U2C ES030158NSF | BIO | Division of Integrative Organismal Systems (IOS) 1920420NSF | BIO | Division of Molecular and Cellular Biosciences (MCB) 11157921United States Department of Agriculture | National Institute of Food and Agriculture (NIFA) 2020-10592
6 · The paper itself

Abstract

Guard cell pairs in the leaf epidermis enclose stomata, microscopic pores mediating CO

Indexed as

ArabidopsisMesophyll CellsPlant StomataSugarsVicia fabaIon TransportLightMetabolomicsPhotosynthesisRed LightSugars

Identifiers

PMID40855242
PMCPMC12449266

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.