ArticleCurrent microbiology2025
Antibiotic Susceptibility Evaluation in Bacterial Infections from Orthopedic Inpatients with Leg Trauma.
Article in Current microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The COVID-19 pandemic has profoundly impacted healthcare delivery systems worldwide, but its impact on orthopedic infection patterns remains unclear. This retrospective comparative study analyzed 173 patients with leg trauma-related orthopedic infections from June 2018 to May 2025, divided into two periods based on China's pandemic control policy changes in December 2022: pre-policy adjustment (n = 86) and post-policy adjustment (n = 87). Our study revealed four major pandemic-driven changes: First, patients were significantly younger (50.6 ± 15.0 vs 52.6 ± 16.1 years, p < 0.001) with dramatically reduced hospital stays (16.9 ± 11.3 vs 28.0 ± 26.2 days, p < 0.001). Second, bacterial ecology shifted markedly, with S. aureus prevalence declining from 53.5% to 41.4% while E. faecium emerged exclusively in the post-policy period (4.6%). Third, antibiotic resistance patterns showed divergent trends: β-lactam resistance improved (40.1% to 30.2%), whereas resistance to fluoroquinolones (24.9% to 36.3%), macrolides (40.0% to 59.2%), and lincosamides (40.8% to 52.5%) increased significantly. Fourth, MRSA prevalence among S. aureus isolates rose from approximately 40% to 45%, although glycopeptides and lipopeptides maintained excellent efficacy (≤ 1.1% resistance). These findings highlight pandemic-driven changes in orthopedic infections, necessitating updated antibiotic protocols and strengthened antimicrobial stewardship.
Indexed as
Identifiers
40855232What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.