Evidence map›Paper›PMID 40855225›Full record

Trial reportAAPS PharmSciTech2025

Voriconazole Loaded Spanlastics: Design, Formulation, Optimization, and Randomized Controlled Clinical Insights for Vulvovaginal Candidiasis Therapy.

Nermin M Sheta, Rehab Nabil Shamma, Raghda R S Hussein, Sara Abdallah Mohamed Salem, Lamiaa N Abdelaty, Mahmoud M Abd El Gawad, Khaled M Abdel-Haleem

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in AAPS PharmSciTech, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nermin M ShetaPharmaceutics and Industrial Pharmacy Department, Faculty of Pharmacy, October 6 University, 6th of October City, Central Axis, Part 1/1, Behind Sixth October City Authority, Giza, 12585, Egypt. nerminsheta@o6u.edu.eg.ORCID http://orcid.org/0000-0002-0375-4946
Rehab Nabil ShammaPharmaceutics & Industrial Pharmacy Department, Faculty of Pharmacy, Cairo University, Giza, Egypt.ORCID http://orcid.org/0000-0002-7635-6842
Raghda R S HusseinClinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.ORCID http://orcid.org/0000-0002-0503-685X
Sara Abdallah Mohamed SalemObstetrics and Gynecology Department, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt.ORCID http://orcid.org/0009-0007-6304-128X
Lamiaa N AbdelatyClinical Pharmacy Department, Faculty of Pharmacy, October 6 University, 6Th of October City, Egypt.ORCID http://orcid.org/0000-0003-0061-4435
Mahmoud M Abd El GawadPharmaceutics and Industrial Pharmacy Department, Faculty of Pharmacy, October 6 University, 6th of October City, Central Axis, Part 1/1, Behind Sixth October City Authority, Giza, 12585, Egypt.ORCID http://orcid.org/0009-0009-0816-0926
Khaled M Abdel-HaleemPharmaceutics and Industrial Pharmacy Department, Faculty of Pharmacy, October 6 University, 6th of October City, Central Axis, Part 1/1, Behind Sixth October City Authority, Giza, 12585, Egypt.ORCID http://orcid.org/0000-0001-7272-2676

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Voriconazole, a potent antifungal agent, has emerged as a promising candidate for managing vulvovaginal candidiasis. The market availability of voriconazole as tablets or injections, along with potential side effects, highlights the need for a successful alternative delivery system. Through comprehensive experimental design, voriconazole-loaded spanlastics were developed using a 3

Indexed as

Antifungal AgentsCandidiasis, VulvovaginalVoriconazoleAdultAnimalsCandidaChemistry, PharmaceuticalFemaleGelsHumansRatsAntifungal AgentsGelsVoriconazoleClinicalClotrimazoleSpanlasticsVoriconazoleVulvovaginal candidiasis/recurrent vaginal candidiasis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.