Evidence map›Paper›PMID 40855107›Full record

ArticleScientific reports2025

Highly sensitive and label-free detection of SARS-CoV-2 proteins via surface plasmon resonance using biofunctionalization with 1 nm thick carbon nanomembranes.

Ghazaleh Eshaghi, David Kaiser, Hamid Reza Rasouli, Rania Ennaciri, Martha Frey, Christof Neumann, Dominik Gary, Tobias Fischer, Katrin Frankenfeld, Andrey Turchanin

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Self-Assembly of Linear Three-Ring Aromatic Thiols on Au(111).The journal of physical chemistry letters · 2026
    Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ghazaleh EshaghiInstitute of Physical Chemistry, Friedrich Schiller University Jena, 07743, Jena, Germany.
David KaiserInstitute of Physical Chemistry, Friedrich Schiller University Jena, 07743, Jena, Germany.
Hamid Reza RasouliInstitute of Physical Chemistry, Friedrich Schiller University Jena, 07743, Jena, Germany.
Rania EnnaciriInstitute of Physical Chemistry, Friedrich Schiller University Jena, 07743, Jena, Germany.
Martha FreyInstitute of Physical Chemistry, Friedrich Schiller University Jena, 07743, Jena, Germany.
Christof NeumannInstitute of Physical Chemistry, Friedrich Schiller University Jena, 07743, Jena, Germany.
Dominik Garyfzmb GmbH, Forschungszentrum für Medizintechnik und Biotechnologie, 99947, Bad Langensalza, Germany.
Tobias Fischerfzmb GmbH, Forschungszentrum für Medizintechnik und Biotechnologie, 99947, Bad Langensalza, Germany.
Katrin Frankenfeldfzmb GmbH, Forschungszentrum für Medizintechnik und Biotechnologie, 99947, Bad Langensalza, Germany.
Andrey TurchaninInstitute of Physical Chemistry, Friedrich Schiller University Jena, 07743, Jena, Germany. andrey.turchanin@uni-jena.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here we report a novel platform for the detection of nucleocapsid (N) and receptor-binding domain (RBD) of spike (S) proteins of SARS-CoV-2 viruses using the surface plasmon resonance (SPR) technique. We demonstrate that the functionalization of SPR sensors with molecular 2D materials - 1 nm thick carbon nanomembranes (CNMs) significantly enhances sensitivity. CNMs terminated with azide linker (N

Indexed as

COVID-19SARS-CoV-2Spike Glycoprotein, CoronavirusSurface Plasmon ResonanceBiosensing TechniquesCarbonHumansLimit of DetectionNanostructuresCarbonSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2BiosensorsCarbon nanomembraneSARS-CoV-2Surface functionalizationSurface plasmon resonanceTwo-dimensional materials

Identifiers

PMID40855107
PMCPMC12378216

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.