Evidence map›Paper›PMID 40855088›Full record

ArticleScientific reports2025

Chemical composition and in vitro bioactivities of hydroalcoholic extracts from Turnera pumilea, Hyptis lantanifolia, and Ageratina popayanensis cultivated in Colombia.

Karina Caballero-Gallardo, Patricia Quintero-Rincón, Elena E Stashenko, Jesus Olivero-Verbel

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Frontiers in veterinary science · 2026
    Article
  3. Article
  4. Cytotoxic and Antimicrobial Activity of theMolecules (Basel, Switzerland) · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Karina Caballero-GallardoFunctional Toxicology Group. School of Pharmaceutical Sciences, Zaragocilla Campus, University of Cartagena, 130014, Cartagena, Colombia. kcaballerog@unicartagena.edu.co.ORCID https://orcid.org/0000-0002-8810-3412
Patricia Quintero-RincónFunctional Toxicology Group. School of Pharmaceutical Sciences, Zaragocilla Campus, University of Cartagena, 130014, Cartagena, Colombia.ORCID https://orcid.org/0000-0003-2469-6279
Elena E StashenkoCenter for Chromatography and Mass Spectrometry CROM-MASS, Research Center for Biomolecules CIBIMOL, School of Chemistry, Universidad Industrial de Santander, Bucaramanga, 680006, Colombia.ORCID https://orcid.org/0000-0001-7052-932X
Jesus Olivero-VerbelEnvironmental and Computational Chemistry Group. School of Pharmaceutical Sciences, Zaragocilla Campus, University of Cartagena, 130014, Cartagena, Colombia.ORCID https://orcid.org/0000-0003-3089-5872

Funding

Minciencias - Programa Orquídeas, mujeres en la ciencia: agentes para la paz (Call No. 935-2023) through the Francisco José de Caldas Fund and from the municipality of Zambrano Bolivar 112721-262-2023Ministry of Science, Technology and Innovation (Minciencias), the Ministry of Education, the Ministry of Industry, Commerce and Tourism, and ICETEX, Programme Ecosistema Científico-Colombia Científica, from the Francisco José de Caldas Fund RC-FP44842-212-2018University of Cartagena Resolution No.02-2024
6 · The paper itself

Abstract

Colombia's strategic location, encompassing diverse climates and ecosystems, enables abundant flora. This environment offers bioprospecting opportunities, emphasizing sustainable plant use. Our main objective was to expand the knowledge of the chemical, pharmacological, and cosmetic potential of three cultivated species, namely, T. pumilea, H. lantanifolia, and A. popayanensis. UHPLC-ESI-Orbitrap-HRMS and quantification of total flavonoid, phenolic, and condensed tannin contents were employed to elucidate the chemical composition. The antioxidant activity and photoprotective capacity were evaluated by spectrophotometry. Calu-1 and HepG2 cells were used to assess cytotoxicity by MTT assay, and early intracellular ROS production was evaluated using an H

Indexed as

Plant ExtractsAntioxidantsColombiaFlavonoidsHep G2 CellsHumansPhenolsReactive Oxygen SpeciesAntioxidantsFlavonoidsPhenolsPlant ExtractsReactive Oxygen SpeciesBiodiversityChemical analysisCosmeceutical and Pharmacological properties

Identifiers

PMID40855088
PMCPMC12378405

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.