Evidence map›Paper›PMID 40855016›Full record

ArticleBiochemical genetics2026

lncRNA EBLN3P Promotes Proliferation, Metastasis and Stemness of Gastric Cancer Cells via miR-141-3p/HMGCS1.

Yang Zong, Jia Shen, Lei Wang, Lifeng Wang, Yuli Chen, Chenxing Ge, Jianfeng Gu, Qi Hu

Abstract read
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In one paragraph

Article in Biochemical genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yang Zong *Department of General Surgery, Changshu Hospital Affiliated to Soochow University, No.1, Shuyuan Street, Yushan Town, Changshu, Suzhou, 215501, China.
Jia Shen *Department of General Surgery, Changshu Hospital Affiliated to Soochow University, No.1, Shuyuan Street, Yushan Town, Changshu, Suzhou, 215501, China.
Lei WangDepartment of General Surgery, Changshu Hospital Affiliated to Soochow University, No.1, Shuyuan Street, Yushan Town, Changshu, Suzhou, 215501, China.
Lifeng WangDepartment of General Surgery, Changshu Hospital Affiliated to Soochow University, No.1, Shuyuan Street, Yushan Town, Changshu, Suzhou, 215501, China.
Yuli ChenDepartment of General Surgery, Changshu Hospital Affiliated to Soochow University, No.1, Shuyuan Street, Yushan Town, Changshu, Suzhou, 215501, China.
Chenxing GeDepartment of General Surgery, Changshu Hospital Affiliated to Soochow University, No.1, Shuyuan Street, Yushan Town, Changshu, Suzhou, 215501, China.
Jianfeng GuDepartment of General Surgery, Changshu Hospital Affiliated to Soochow University, No.1, Shuyuan Street, Yushan Town, Changshu, Suzhou, 215501, China. jscsgjf@sina.cn.
Qi HuDepartment of General Surgery, Changshu Hospital Affiliated to Soochow University, No.1, Shuyuan Street, Yushan Town, Changshu, Suzhou, 215501, China. surhuqi@163.com.

Funding

Basic research on medical application of Changshu Science and Technology Program CSWSQ202301Changshu Clinical Medical Expert Team Introduction Project CSYJTD202101Changshu Science and Technology Program (Social Development) Project CS202120Key discipline project of Changshu No. CSZDXK202301"National tutorial system" training project of Suzhou Qngg2022039
6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) have become an essential factor in gastric cancer (GC) initiation and metastasis. This study is aimed to uncover the functional significance of EBLN3P in GC. In GC, EBLN3P and HMGCS1 was significantly increased. In contrast, miR-141-3p was decreased. Localization assay revealed that EBLN3P primarily localized in the cytoplasm rather than the nucleus. In MKN28 and SGC7901 cells, EBLN3P knockdown suppressed cell proliferation, metastasis and stemness. On the contrary, overexpression of EBLN3P facilitated these cellular processes. The EBLN3P/miR-141-3p/HMGCS1 axis was identified to play crucial functions in GC progression.

Indexed as

Cell ProliferationMicroRNAsNeoplastic Stem CellsRNA, Long NoncodingStomach NeoplasmsCell Line, TumorCell MovementGene Expression Regulation, NeoplasticHumansNeoplasm MetastasisMicroRNAsMIRN141 microRNA, humanRNA, Long NoncodingEBLN3PGastric cancerHMGCS1miR-141-3pStemness properties

Identifiers

PMID40855016

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.