Evidence map›Paper›PMID 40854999›Full record

ArticleSurgical endoscopy2025

Back-table specimen scanning using gantry-free hybrid hSPECT/LiDAR imaging: a feasibility study during PSMA-radioguided surgery.

Giusi Pisano, Matthias N van Oosterom, Vera A Ottens, Anne-Claire Berrens, Leon J Slof, Berkay A Çakal, Daphne D D Rietbergen, Henk G van der Poel, Pim J van Leeuwen, Fijs W B van Leeuwen

Abstract read
In one paragraph

Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Nuclear medicine in the operating room: present and future.The British journal of radiology · 2026
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giusi PisanoInterventional Molecular Imaging Laboratory, Leiden University Medical Centre, Leiden, The Netherlands. g.pisano@lumc.nl.ORCID http://orcid.org/0000-0001-9627-5065
Matthias N van OosteromInterventional Molecular Imaging Laboratory, Leiden University Medical Centre, Leiden, The Netherlands.
Vera A OttensInterventional Molecular Imaging Laboratory, Leiden University Medical Centre, Leiden, The Netherlands.
Anne-Claire BerrensInterventional Molecular Imaging Laboratory, Leiden University Medical Centre, Leiden, The Netherlands.
Leon J SlofInterventional Molecular Imaging Laboratory, Leiden University Medical Centre, Leiden, The Netherlands.
Berkay A ÇakalInterventional Molecular Imaging Laboratory, Leiden University Medical Centre, Leiden, The Netherlands.
Daphne D D RietbergenInterventional Molecular Imaging Laboratory, Leiden University Medical Centre, Leiden, The Netherlands.
Henk G van der PoelDepartment of Urology, Netherlands Cancer Institute-Antoni Van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Pim J van LeeuwenDepartment of Urology, Netherlands Cancer Institute-Antoni Van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Fijs W B van LeeuwenInterventional Molecular Imaging Laboratory, Leiden University Medical Centre, Leiden, The Netherlands.

Funding

Nederlandse Organisatie voor Wetenschappelijk Onderzoek NWO-KIC grant (KICH1.ST03.21.030)
6 · The paper itself

Abstract

introductionProstate-specific membrane antigen (PSMA) targeted precision surgery is becoming increasingly popular. However, the relatively low levels of PSMA-receptor expression and background signal can hinder in vivo lesion detection and margin evaluation. Back-table imaging (ex vivo) potentially provides a means to confirm surgical accuracy. For

methodsWe included samples from 5 prostate cancer patients undergoing primary or salvage robot-assisted resection of

resultshSPECT/LiDAR imaging provided accurate representation of the

conclusionWe present the technical feasibility of a new 3D hybrid modality (hSPECT/LiDAR) that allows back-table assessment of surgical specimens from the already well validated robotic

Indexed as

ProstatectomyProstatic NeoplasmsSurgery, Computer-AssistedTomography, Emission-Computed, Single-PhotonAgedAntigens, SurfaceFeasibility StudiesGlutamate Carboxypeptidase IIHumansMaleMiddle AgedRadiopharmaceuticalsRobotic Surgical ProceduresAntigens, SurfaceFOLH1 protein, humanGlutamate Carboxypeptidase IIRadiopharmaceuticalsImage-guided surgeryProstate cancerPSMA SPECT/CT/LiDARRadioguided surgerySpecimen scanningSurface scanning

Identifiers

PMID40854999
PMCPMC12500833

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.