ArticleInternational journal of obesity (2005)2025
Visceral adipose tissue during pregnancy in women with overweight or obesity and offspring metabolic health.
Article in International journal of obesity (2005), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPre-pregnancy obesity is linked to an increased risk of adverse maternal and neonatal outcomes, and an increased likelihood of offspring obesity later in life. Accumulation of visceral adipose tissue (VAT) has been reported to be more detrimental to health outcomes than generalized obesity. Therefore, we investigated the association between maternal VAT and the metabolic health of offspring at birth.
methodsThis study was a secondary analysis of a dietary randomized controlled trial. Magnetic resonance imaging was performed in gestational weeks (GW) 15, 32, and at birth in a cohort of 119 pregnant women with a pre-pregnancy body mass index ranging from 28-45 kg/m
resultsAbsolute maternal VAT during pregnancy was not associated with birthweight; however, women who experienced a reduction in VAT volume during pregnancy entered pregnancy with a higher VAT volume and gave birth to heavier infants by 161 grams (95% CI, 15; 307, P = 0.031) compared to those who experienced an increase in VAT during pregnancy. Maternal VAT in GW 15 and at birth was associated with increased insulin concentrations in the offspring by 0.25 pmol/L (95% CI, 0.03; 0.46, P = 0.026) and 0.23 pmol/L (95% CI, 0.02; 0.44, P = 0.035), respectively, per 1 cm
conclusionMaternal VAT, and particularly its change during pregnancy, may influence the fetal metabolic environment, impacting insulin availability and potentially fetal growth in healthy women with overweight or obesity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.