Evidence map›Paper›PMID 40854869›Full record

ArticleOrganic letters2025

Irradiation of Bifunctional Masked Ketone Pro-Aromatics Unveils Autoinductive Autocatalysis via Electron Donor-Acceptor (EDA) Complexes.

Cheng-Lin Chan, Yong-Ting Tsao, Aira Shayne Paculba, Pei-Shan Lin, Zong-Nan Tsai, Hung-Hsuan Chiu, Risa Kunitake, Ming-Jia Chiu, Chun-Chi Yeh, Cheng-Chau Chiu and 1 more

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In one paragraph

Article in Organic letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Cheng-Lin ChanDepartment of Chemistry, National Sun Yat-sen University, Kaohsiung 804201, Taiwan (R.O.C.).
Yong-Ting TsaoDepartment of Chemistry, National Sun Yat-sen University, Kaohsiung 804201, Taiwan (R.O.C.).
Aira Shayne PaculbaDepartment of Chemistry, National Sun Yat-sen University, Kaohsiung 804201, Taiwan (R.O.C.).
Pei-Shan LinDepartment of Chemistry, National Sun Yat-sen University, Kaohsiung 804201, Taiwan (R.O.C.).
Zong-Nan TsaiDepartment of Chemistry, National Sun Yat-sen University, Kaohsiung 804201, Taiwan (R.O.C.).
Hung-Hsuan ChiuDepartment of Chemistry, National Sun Yat-sen University, Kaohsiung 804201, Taiwan (R.O.C.).
Risa KunitakeDepartment of Chemistry, National Sun Yat-sen University, Kaohsiung 804201, Taiwan (R.O.C.).
Ming-Jia ChiuDepartment of Chemistry, National Sun Yat-sen University, Kaohsiung 804201, Taiwan (R.O.C.).
Chun-Chi YehDepartment of Chemistry, National Sun Yat-sen University, Kaohsiung 804201, Taiwan (R.O.C.).
Cheng-Chau ChiuDepartment of Chemistry, National Sun Yat-sen University, Kaohsiung 804201, Taiwan (R.O.C.).ORCID 0000-0002-2106-8181
Hsuan-Hung LiaoDepartment of Chemistry, National Sun Yat-sen University, Kaohsiung 804201, Taiwan (R.O.C.).ORCID 0000-0001-7825-2425

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We disclose an autocatalytic electron donor-acceptor (EDA) strategy by reutilizing redox auxiliary byproducts as in situ acceptors, enabling an external initiator-free activation of pro-aromatic dihydroquinazolinones (DHQZs). Spectroscopic and DFT data support the Lewis acid-enhanced aggregate formation where DHQZ serves as both donor and latent acceptor through its quinazolinone byproduct. Kinetic studies reveal a kinetic profile specifically representing autoinductive autocatalysis. This platform enables Giese-type acylation/alkylation, desulfonylation, and Minisci reactions, forging C-C, C-N, C-S, and C-Se bonds under mild conditions.

Identifiers

PMID40854869
PMCPMC12418491

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.