SynthesisBMJ open respiratory research2025
Enhanced detection of patients with previous COVID-19: superiority of the double diffusion technique.
Synthesis in BMJ open respiratory research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- The Role of DLNO in the Functional Assessment of Patients with Idiopathic Pulmonary Fibrosis.Medicina (Kaunas, Lithuania) · 2026Observational
- Emphysema Detection in Smokers: Diffusing Capacity for Nitric Oxide Beats Diffusing Capacity of Carbon Monoxide-Based Models.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2025Article
- Pulmonary diffusing capacity and dyspnoea following COVID-19: Insights from multicentre datasets.Data in brief · 2025Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPersistent pulmonary dysfunction is common after COVID-19, yet traditional assessments using carbon monoxide diffusing capacity (DLCO) alone may miss alveolar-capillary impairment.
objectiveTo determine whether combining nitric oxide (DLNO DESIGN AND
methodsWe conducted an individual participant data meta-analysis using hierarchical mixed-effects modelling. The dataset included 572 COVID-19 survivors and 72 matched controls from six European centres. Lung function metrics-including spirometry, total lung capacity, DLNO
resultsThe number of days between SARS-CoV-2 diagnosis and testing did not affect any of the measured z-scores. Summed DLNO
conclusionSummed DLNO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.