ArticleAJNR. American journal of neuroradiology2026
Mapping Regional Brain Total Sodium Concentration Using Anatomically Guided Reconstruction of Dual-Echo Sodium-23 MRI: Moving toward Improved Accuracy and Precision.
Alaleh Alivar, Georg Schramm, Yongxian Qian, Hugo Lefer, Johan Nuyts, Fernando Boada, Yvonne W Lui
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In one paragraphArticle in AJNR. American journal of neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
7 authors.
Alaleh AlivarFrom the Department of Radiology (A.A., Y.Q., H.L., Y.W.L.), Bernard and Irene Schwartz Center for Biomedical Imaging, New York University Grossman School of Medicine, New York, New York.ORCID 0000-0002-9123-1079 Georg SchrammDepartment of Imaging and Pathology (G.S., J.N.), KU Leuven, Belgium.
Yongxian QianFrom the Department of Radiology (A.A., Y.Q., H.L., Y.W.L.), Bernard and Irene Schwartz Center for Biomedical Imaging, New York University Grossman School of Medicine, New York, New York.
Hugo LeferFrom the Department of Radiology (A.A., Y.Q., H.L., Y.W.L.), Bernard and Irene Schwartz Center for Biomedical Imaging, New York University Grossman School of Medicine, New York, New York.
Johan NuytsDepartment of Imaging and Pathology (G.S., J.N.), KU Leuven, Belgium.
Fernando BoadaRadiological Sciences Laboratory (F.B.), Stanford University, School of Medicine, Stanford, California.
Yvonne W LuiFrom the Department of Radiology (A.A., Y.Q., H.L., Y.W.L.), Bernard and Irene Schwartz Center for Biomedical Imaging, New York University Grossman School of Medicine, New York, New York yvonne.lui@nyulangone.org.ORCID 0000-0002-9984-9164 Funding
TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Daniel K Sodickson · 2014 to 2026
$19.3MOptimized Sodium MR Imaging at Clinical Field Strength to Study in vivo Sodium Signal in Mild Traumatic Brain InjuryR01NS131458 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Yvonne W Lui, Yongxian Qian · 2023 to 2026
$2.6MAnatomically Guided Sodium MRI: Accurately Monitoring Chronic Ion Pump Dysfunction in the Human BrainR01EB031199 · NIBIB · STANFORD UNIVERSITY · PI BOADA, FERNANDO E · 2022 to 2025
$2.3MUnderstanding CSF Clearance in Aging and Alzheimerâs Brain Through Dynamic Sodium MRI - Resubmission - 1R01AG067502 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI QIAN, YONGXIAN · 2024 to 2025
$1.5MNIA NIH HHS R01 AG067502NIBIB NIH HHS P41 EB017183NIBIB NIH HHS R01 EB031199NINDS NIH HHS R01 NS131458
6 · The paper itselfAbstract
background and purposeSodium ( MATERIALS AND
methodsThirty-four healthy subjects were studied by using a 3T clinical MRI scanner with a dual-tuned (
resultsThe WM erosion experiments confirmed that TSC
conclusionsThe AGR helps sodium quantification in healthy human brains by reducing the PVE and variance of TSC in noncortical brain regions. Our normative values of TSC in the brain regions set the stage to better understand derangements of
Indexed as
BrainBrain ChemistryMagnetic Resonance ImagingSodiumAdultAlgorithmsFemaleHumansMaleMiddle AgedReproducibility of ResultsSensitivity and SpecificitySodium IsotopesYoung AdultSodiumSodium Isotopes
Identifiers
PMID40854686
PMCPMC12867045
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