ArticleThe American journal of clinical nutrition2025
Anthropometric indices for predicting incident cardiovascular disease: a 13-year follow-up study in a Japanese population.
Article in The American journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Association between body roundness index and progression of cardio-renal-metabolic diseases using multistate models.GeroScience · 2026Article
- A Literature Review on the Waist Circumference Criteria for Metabolic Syndrome in Japan: Evidence and Implications for Cardiovascular Risk Stratification.Journal of atherosclerosis and thrombosis · 2026Review
- Change of frailty index and anthropometric indices in patients with chronic obstructive pulmonary disease.BMC pulmonary medicine · 2026Article
- Triglyceride-glucose-related indices and cardiovascular outcomes in individuals with pre-frailty or frailty: insights from a prospective cohort analysis using UK Biobank data.Cardiovascular diabetology · 2026Article
- Independent and joint associations of a body shape index and cardiorespiratory fitness with executive function in adolescents: a cross-sectional study in China.Frontiers in nutrition · 2026Article
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12 authors.
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Abstract
backgroundTo our knowledge, no previous study has compared the predictive capacity of various anthropometric indices of cardiovascular disease (CVD) risk in East Asians.
objectiveThis study aimed to compare which anthropometric indices have a greater impact on CVD in the Japanese population.
methodsData from a health checkup program conducted by the Panasonic Corporation between 2008 and 2021, including 160,656 participants, were analyzed. The primary outcome was the incidence of 3-point major adverse cardiac events (MACEs), including cardiovascular death, nonfatal coronary artery disease, and nonfatal stroke. Cox proportional hazards models and time-dependent receiver operating characteristic (ROC) analyses were used to evaluate the associations between 5 anthropometric indices [body mass index (BMI), waist circumference (WC), a body shape index (ABSI), body roundness index (BRI), and waist-to-height ratio (WHtR)] and incident MACE, stratified by gender.
resultsMultivariate analysis showed that all anthropometric indices were associated with incident MACE in males: BMI {hazard ratio (HR) per SD 1.15, [95% confidence interval (CI): 1.11, 1.18]}, WC [1.15, (1.12, 1.19)], ABSI [1.06, (1.02, 1.09)], BRI [1.16, (1.13, 1.20)], and WHtR [1.17, (1.13, 1.21)]. In females, no significant associations were found between any anthropometric indices and the incident MACE. Among males, the areas under the curve values for BRI and WHtR [both 0.608 (95% CI: 0.598, 0.618)] were higher than those for BMI [0.586 (5% CI: 0.576, 0.596)], WC [0.598 (95% CI: 0.588, 0.608)], and ABSI [0.563 (95% CI: 0.552, 0.573)], with the values for BRI and WHtR being identical. The optimal cut-off values for predicting CVD were 3.250 for BRI and 0.494 for WHtR.
conclusionsBRI and WHtR were more significant predictors of incident CVD in Japanese males >13 y of follow-up than BMI, WC, and ABSI. The identified cutoffs may help improve risk stratification and support early preventive interventions to reduce cardiovascular disease risk.
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