ArticleEuropean biophysics journal : EBJ1985
Time-resolved X-ray scattering study of actin polymerization from profilactin.
Article in European biophysics journal : EBJ, 1985. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 11 citations in OpenAlex.
- The actin depolymerizing factor (ADF)/cofilin signaling pathway and DNA damage responses in cancer.International journal of molecular sciences · 2015Review
- The effect of organic cryosolvents on actin structure: studies by small angle X-ray scattering.European biophysics journal : EBJ · 1992Article
- Synchrotron x-ray diffraction studies of actin structure during polymerization.Proceedings of the National Academy of Sciences of the United States of America · 1987Article
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Authors and funding
4 authors at 2 institutions in 3 countries.
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Abstract
The polymerization of actin in solutions of purified calf spleen actin or profilactin (1-10 mg . ml-1) was followed by synchrotron radiation X-ray solution scattering. At the concentration used, polymerization of actin from profilactin or actin occurs without any lag phase. It is shown by a combination of solution scattering, model calculations and electron microscopy that contrary to the conclusions from previous viscometry studies, filaments form without any lag phase in profilactin solution but aggregate in bundles or networks. This phenomenon is independent of the method used to induce polymerization: slow temperature increase, temperature jump in the presence of polymerizing salts or fast mixing with salt. This aggregation explains the lower final viscosity levels, as compared to actin solutions, observed during the polymerization of actin from profilactin.
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