ArticleEuropean biophysics journal : EBJ1985
Interfacial instability and the agglutination of erythrocytes by polylysine.
Article in European biophysics journal : EBJ, 1985. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 33 citations in OpenAlex.
- Methylated N-(4-N,N-dimethylaminobenzyl) chitosan, a novel chitosan derivative, enhances paracellular permeability across intestinal epithelial cells (Caco-2).AAPS PharmSciTech · 2008Article
- Topographical pattern dynamics in passive adhesion of cell membranes.Biophysical journal · 2004Article
- Localized contact formation by erythrocyte membranes: electrostatic effects.Biophysical journal · 1995Article
- Influence of polymer concentration and molecular weight and of enzymic glycocalyx modification on erythrocyte interaction in dextran solutions.European biophysics journal : EBJ · 1993Article
- Detachment of agglutinin-bonded red blood cells. II. Mechanical energies to separate large contact areas.Biophysical journal · 1991Article
- Contact patterns in concanavalin A agglutinated erythrocytes.Cell biophysics · 1991Article
- Spreading of wheat germ agglutinin-induced erythrocyte contact by formation of spatially discrete contacts.Cell biophysics · 1990Article
- Energetics of cell-cell and cell-biopolymer interactions.Cell biophysics · 1989Article
- Spatially periodic discrete contact regions in polylysine-induced erythrocyte-yeast adhesion.Cell biophysics · 1988Article
- Mechanisms of successive modes of erythrocyte stability and instability in the presence of various polymers.Cell biophysics · 1988Article
- Real time observations of polylysine, dextran and polyethylene glycol induced mutual adhesion of erythrocytes held in suspension in an ultrasonic standing wave field.European biophysics journal : EBJ · 1987Article
- Morphology of cell-substratum adhesion. Influence of receptor heterogeneity and nonspecific forces.Cell biophysicsReview
- Article
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3 authors.
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Abstract
Human erythrocytes have been exposed to polylysine of molecular weight range 4 to 220 kDa and concentration range 0.5 to 2,000 micrograms/ml at 37 degrees C. Threshold concentrations for cell agglutination by the polycation have been determined for the samples of different molecular weight. Light and electron micrographs show that, in the erythrocyte agglutinates, cell-cell contact is generally made only at discrete, spatially periodic, regions which are distributed over a significant part of the cell surface. The average spacing between contact regions is 0.83 micron. The cell membrane has a wavy profile between contact regions. Agglutination occurs only in cell samples whose electrophoretic mobility is significantly altered by polylysine and, in agreement with a previous report, occurs even when the electrophoretic mobility reaches high positive values. The electrophoretic mobility data implies that agglutination requires some protrusion of polylysine from the cell glycocalyx. We discuss how a resulting net attractive intercellular force could act to destabilize the aqueous layer between two cells, allowing surface wave growth which results in spatially periodic contact regions. Examples of situations where cell and membrane contact might by explained by the general concept of interfacial instability are discussed.
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