Evidence map›Paper›PMID 40854008›Full record

SynthesisMovement disorders clinical practice2026

Vestibular Dysfunction in Parkinson's Disease: A Systematic Review of Signs and Symptoms.

Francisco Rosado-Martins, Beatriz Santos, Cláudia M Costa, Tiago Eça, Raquel Bouça-Machado, Joaquim J Ferreira

Abstract readSystematic Review
In one paragraph

Synthesis in Movement disorders clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Francisco Rosado-MartinsCNS-Campus Neurológico, Torres Vedras, Portugal.
Beatriz SantosCNS-Campus Neurológico, Torres Vedras, Portugal.
Cláudia M CostaEscola Superior de Saúde Atlântica, Barcarena, Portugal.
Tiago EçaCNS-Campus Neurológico, Torres Vedras, Portugal.
Raquel Bouça-MachadoLaboratory of Clinical Pharmacology and Therapeutics, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
Joaquim J FerreiraCNS-Campus Neurológico, Torres Vedras, Portugal.ORCID https://orcid.org/0000-0003-3950-5113

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the growing interest in the link between Parkinson's disease (PD) neuropathology and vestibular system, there is still a lack of consensus about the presence of vestibular dysfunctions in PD.

objectiveThis review aims to identify vestibular signs and symptoms reported in PD patients and to summarize and critically appraise the measurement tools used to assess them.

methodsWe searched at MEDLINE, Web of Science, Scopus, and PEDro databases until June 2023. All experimental or observational studies focused on evaluating vestibular signs or symptoms in PD patients were included. For clinical appraise of measurement tools previously published criteria were applied.

resultsIn total, 104 studies met the inclusion criteria. A total of 238 vestibular signs were identified, with the most frequently reported being nystagmus (n = 47, 19.7%) central oculomotor abnormalities (n = 47, 19.7%), vestibular evoked myogenic potentials impairments (n = 39, 16.4%), and postural control impairments (n = 37, 15.5%). A total of 27 vestibular symptoms were identified, with dizziness (n = 17, 63.0%) being the most frequently reported. Of the most commonly used, 6 were classified as "recommended," 14 as "suggested," and 5 as "listed."

conclusionsOur findings raise awareness that vestibular signs and symptoms may be present in PD and should therefore be assessed comprehensively using the most suitable measurement tools. Future studies should focus on investigating the relationship between PD and the vestibular system, the progression of these signs and symptoms across disease stages, and the development of a standardized vestibular assessment protocol for PD to improve clinical management of these symptoms.

Indexed as

Parkinson DiseaseVestibular DiseasesDizzinessHumansPostural BalanceVestibular Evoked Myogenic Potentialscentral oculomotor abnormalitiesdizzinessnystagmuspostural control impairmentsvestibular evoked myogenic potentials impairments

Identifiers

PMID40854008
PMCPMC12911527

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.