ArticleMovement disorders clinical practice2025
An Exploration of the High Prevalence of Parkinson's Disease in a Rural Area of North West England.
Article in Movement disorders clinical practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Mapping the Parkinson's pandemic: Unveiling and addressing the global burden.Journal of Parkinson's disease · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGlobally the prevalence of Idiopathic Parkinson's Disease (IPD) is rising. Increasing recognition is being given to the influence of environmental factors on this rise, although the precise impact of such factors remains poorly understood. We need accurate ways of measuring prevalence to understand regional and global trends.
objectivesTo use case finding methodology to measure the crude, and age adjusted, prevalence of IPD in a rural area of North West England, and to describe the difference in results with those obtained using electronic record searching alone to understand the accuracy of such methods. To compare prevalence between subgroups to build hypotheses that could guide further research.
methodsLocal Parkinson's service records from several sources were searched electronically and manually reviewed against validated diagnostic criteria. Figures were age adjusted according to the national denominator population.
resultsThe age adjusted prevalence of IPD was 201/100,000 (95% CI 186-217), higher than in any other published UK study using similar case finding methods. Numbers were higher using electronic diagnostic code searching alone, which may over estimate prevalence. No significant difference was seen between rural and urban areas, relative risk 0.92 (95% CI 0.80-1.06), although there was a trend to higher prevalence in historically industrial coastal areas.
conclusionsThis study highlights some of the pitfalls in using large healthcare datasets to measure IPD prevalence. Overall, the prevalence of IPD is high in this predominantly rural area, and exhibits prevalence trends that warrant further investigation in relation to genetic and environmental factors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.