Evidence map›Paper›PMID 40853994›Full record

ArticlePloS one2025

Comprehensive genomic analysis of Xenorhabdus bovienii strain MEL2.2.

Wipanee Meesil, Liam K R Sharkey, Sacha J Pidot, Aunchalee Thanwisai

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wipanee MeesilDepartment of Microbiology and Parasitology, Faculty of Medical Science, Naresuan University, Phitsanulok, Thailand.
Liam K R SharkeyDepartment of Microbiology and Immunology, Doherty Institute, 792 Elizabeth Street, Melbourne, Australia.
Sacha J PidotDepartment of Microbiology and Immunology, Doherty Institute, 792 Elizabeth Street, Melbourne, Australia.
Aunchalee ThanwisaiDepartment of Microbiology and Parasitology, Faculty of Medical Science, Naresuan University, Phitsanulok, Thailand.ORCID https://orcid.org/0000-0001-7842-2850

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genome sequences of entomopathogenic bacteria and their functional analyses provide valuable insights for genetic engineering to enhance their use as biocontrol agents. In this study, we examine the draft genome of Xenorhabdus bovienii strain MEL2.2, which was isolated from entomopathogenic nematodes in Melbourne, Australia. The genome of Xenorhabdus strain MEL2.2 spans approximately 4.4 million base pairs and has a G + C content of 44.8%, aligning with known characteristics of the genus. Within the genome, 3,823 protein-coding genes were identified. Functional analysis revealed genes associated with nematode symbiosis and insect virulence. Moreover, 15 biosynthetic gene clusters (BGCs) were detected, potentially responsible for synthesizing various secondary metabolites. Comparative genomic analysis indicated a combination of conserved and strain-specific genes when compared to other Xenorhabdus bovienii strains, suggesting genetic traits that may enhance MEL2.2's adaptability and pathogenicity. Altogether, these findings offer a foundation for exploring the strain's utility in further applications.

Indexed as

Genome, BacterialGenomicsXenorhabdusAnimalsBase CompositionMultigene FamilyPhylogenySymbiosisVirulence

Identifiers

PMID40853994
PMCPMC12377575

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.