Evidence map›Paper›PMID 40853977›Full record

ArticleJournal of the American Chemical Society2025

Diversity-Oriented Method Development: Multifunctional Homoallylic Amines and Azabicyclooctanes Bearing a Bridgehead Enamine.

Zoé C Mueller, Ryan P Ponzi, Xin Zhi Sui, Peng Liu, Amir H Hoveyda

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zoé C MuellerDepartment of Chemistry, Boston College, Merkert Chemistry Center, Chestnut Hill, Massachusetts 02467, United States.
Ryan P PonziDepartment of Chemistry, Boston College, Merkert Chemistry Center, Chestnut Hill, Massachusetts 02467, United States.
Xin Zhi SuiDepartment of Chemistry, Boston College, Merkert Chemistry Center, Chestnut Hill, Massachusetts 02467, United States.ORCID 0000-0001-7435-2381
Peng LiuDepartment of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.ORCID 0000-0002-8188-632X
Amir H HoveydaDepartment of Chemistry, Boston College, Merkert Chemistry Center, Chestnut Hill, Massachusetts 02467, United States.ORCID 0000-0002-1470-6456

Funding

New Catalysts, Strategies and Methods for Stereoselective Chemical SynthesisR35GM130395 · NIGMS · BOSTON COLLEGE · PI AMIR H HOVEYDA · 2019 to 2026
$4.4M
Computational Models for Reactivity and Selectivity in Transition Metal-Catalyzed Olefin FunctionalizationR35GM128779 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Peng Liu · 2018 to 2026
$2.9M
CryoProbe-enabled Bruker AVANCE NEO 500 MHz NMR SpectrometerS10OD026910 · OD · BOSTON COLLEGE · PI JAYASUNDERA, THUSITHA · 2021 to 2021
$1000k
Bruker D8 VENTURE DiffractometerS10OD030360 · OD · BOSTON COLLEGE · PI LI, BO · 2022 to 2022
$428k
NIGMS NIH HHS R35 GM128779NIGMS NIH HHS R35 GM130395NIH HHS S10 OD026910NIH HHS S10 OD030360
6 · The paper itself

Abstract

Two methods, designed primarily for applications in diversity-oriented synthesis (DOS), are introduced. The first is a Cu-H-catalyzed multicomponent process that involves a nitrile and a trisubstituted allenyl boronate. The first set of products are homoallylic α-secondary NH

Identifiers

PMID40853977
PMCPMC13386541

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.