Evidence map›Paper›PMID 40853954›Full record

ArticlePloS one2025

Exploring the consistency, quality and challenges in manual and automated coding of free-text diagnoses from hospital outpatient letters.

Warren Del-Pinto, George Demetriou, Meghna Jani, Rikesh Patel, Leanne Gray, Alex Bulcock, Niels Peek, Andrew S Kanter, William G Dixon, Goran Nenadic

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Warren Del-PintoDepartment of Computer Science, University of Manchester, Manchester, United Kingdom.ORCID https://orcid.org/0000-0003-3307-9432
George DemetriouDepartment of Computer Science, University of Manchester, Manchester, United Kingdom.
Meghna JaniCentre for Epidemiology Versus Arthritis, University of Manchester, Manchester, United Kingdom.
Rikesh PatelManchester University NHS Foundation Trust, Manchester, United Kingdom.
Leanne GrayUniversity Hospitals of Morecambe Bay NHS Foundation Trust, Kendal, United Kingdom.
Alex BulcockThe Northern Care Alliance NHS Foundation Trust, Salford, United Kingdom.
Niels PeekDivision of Informatics, Imaging and Data Science, University of Manchester, Manchester, United Kingdom.ORCID https://orcid.org/0000-0002-6393-9969
Andrew S KanterIntelligent Medical Objects, Inc., Northbrook, Illinois, United States of America.
William G DixonCentre for Epidemiology Versus Arthritis, University of Manchester, Manchester, United Kingdom.ORCID https://orcid.org/0000-0001-5881-4857
Goran NenadicDepartment of Computer Science, University of Manchester, Manchester, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical coding is the process of extracting key information contained within clinical free-text and representing this information using standardised clinical terminologies. In doing so, unstructured text is transformed into structured data that can be retrieved and analysed more effectively. This process is essential to improving direct care, supporting communication between clinicians and enabling clinical research. However, manual clinical coding is difficult and time consuming, motivating the development and use of natural language processing for automated coding. This work evaluates the quality and consistency of both manual and automated coding of diagnoses from hospital outpatient letters. Using 100 randomly selected letters, two human clinicians performed coding of diagnosis lists to SNOMED CT. Automated coding was also performed using IMO's Concept Tagger. A gold standard was constructed by a panel of clinicians from a subset of the annotated diagnoses. This was used to evaluate the quality and consistency of manual and automated coding via (1) a distance-based metric, treating SNOMED CT as a graph, and (2) a qualitative metric agreed upon by the panel of clinicians. Correlation between the two metrics was also evaluated. Comparing human and computer-generated codes to the gold standard, the results indicate that humans slightly out-performed automated coding, while both performed notably better when there was only a single diagnosis contained in the free-text description. Automated coding was considered acceptable by the panel of clinicians in approximately 90% of cases.

Indexed as

Clinical CodingOutpatientsHumansNatural Language ProcessingSystematized Nomenclature of Medicine

Identifiers

PMID40853954
PMCPMC12377573

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.