ArticlePloS one2025
Neighborhood context, genetic influences, and life satisfaction: Evidence from the German twin family panel.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Both genetic influences and neighborhood environments play a role in shaping life satisfaction. However, research examining gene-environment interactions (GxE) in this context remains limited. This study investigates how neighborhood deprivation moderates the effects of genetic influences on life satisfaction. Using data from 760 dizygotic (DZ) twin pairs in the German Twin Family Panel (TwinLife), we apply twin fixed-effect models to estimate GxE effects. Results indicate that a Polygenic index (PGI) for subjective well-being is positively associated with life satisfaction. Notably, this association is strongest among individuals living in moderately deprived neighborhoods, and weaker in both highly deprived and less deprived areas. Thus, there are signs of compensation in less deprived areas and, particularly, diathesis-stress/triggering in highly deprived areas.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.