ArticleJMIR pediatrics and parenting2025
Effects of Cold and Vibration on Venipuncture Pain Management in Children Aged 2-7 Years Old: Randomized Controlled Trial.
Article in JMIR pediatrics and parenting, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Strategies to Address Difficult Venous Access in Blood Sampling: A Comprehensive Meta-Analysis.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Dynamic assessment of pain, fear, and physiological stress during pediatric intravenous cannulation: a randomized controlled trial of virtual reality distraction.BMC nursing · 2026Article
- Combined use of EMLA cream and Buzzy for peripheral intravenous cannulation in children: a randomized controlled trial.Frontiers in pediatrics · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The pain resulting from venipuncture is one of the primary sources of stress during childhood and can have adverse effects on children. The Buzzy device can play an important role in alleviating the pain of venipuncture in children. Objective: The aim of this study is to investigate the independent and combined effects of cold and vibration in reducing venipuncture pain and resistance behavior in children aged 2-7 years. Methods: A total of 130 children who underwent venipuncture were randomly assigned to 4 groups: 32 in the control group, 30 in the external cold group, 37 in the vibration group, and 31 in the cold combined with vibration group. The cold, vibration, and cold combined with vibration interventions used the Buzzy device. Nurses used the Face, Legs, Activity, Cry, Consolability Pain Behavior Scale and the Children's Behavior Scale to assess pain and resistance behaviors before and during the venipuncture. Results: Compared with the control group, the cold group, vibration group, and cold combined with vibration group experienced milder pain and demonstrated weaker resistance behavior (P<.05). Pairwise comparison results showed that the combination group was superior to the vibration group (P<.05). Conclusions: External cold and vibration are effective in reducing procedural pain and improving compliance in children aged 2-7 years undergoing venipuncture. The cold combined with vibration has a synergistic effect, and the effect is better than vibration only.
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Registered trials
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