Evidence map›Paper›PMID 40853462›Full record

ReviewNeuroradiology2025

Efficacy and safety of Derivo embolization device in intracranial aneurysms: A systematic review and Meta-Analysis.

Bardia Hajikarimloo, Salem M Tos, Abhishek Saha, Ibrahim Mohammadzadeh, Ali Mortezaei, Rana Hashemi, Dorsa Najari, Azin Ebrahimi, Adam A Dmytriw, Mohammad Amin Habibi

Abstract readReview
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In one paragraph

Review in Neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bardia HajikarimlooNeurological Surgery, University of Virginia, Charlottesville, USA. bardii47@yahoo.com.
Salem M TosNeurological Surgery, University of Virginia, Charlottesville, USA.
Abhishek SahaDepartment of Neuroradiology, Oxford University Hospitals NHS Foundation Trust, Nuffield Departments of Clinical Neurosciences and Surgical Sciences, University of Oxford, Oxford, UK.
Ibrahim MohammadzadehNeurological Suregry, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran.
Ali MortezaeiNeurological Suregry, Gonabad University of Medical Sciences, Gonābād, Islamic Republic of Iran.
Rana HashemiNeurological Suregry, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran.
Dorsa NajariNeurological Suregry, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran.
Azin EbrahimiNeurological Suregry, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran.
Adam A DmytriwNeuroendovascular Program, Brigham and Womens Hospital, Boston, USA. adam.dmytriw@gmail.com.
Mohammad Amin HabibiNeurological Surgery, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDerivo embolization device (DED) is a second-generation flow diverter (FD) that has been increasingly used in the management of intracranial aneurysms (IAs). DEDs consist of 48 nitinol wires with an inner platinum core and a blue-colored coating of oxides and oxynitrides, which mitigates these FDs' thrombogenicity. This systematic review and meta-analysis evaluate the efficacy and safety of DED in IAs.

methodsOn February 25, 2025, a comprehensive search was conducted across PubMed, Embase, Scopus, and Web of Science in accordance with PRISMA guidelines. Studies reporting clinical and radiological outcomes of DED were included.

resultsThirteen studies involving 1125 patients and 1338 aneurysms were included. The meta-analysis revealed a pooled complete occlusion rate of 83% (95% CI: 79%-87%), an adequate occlusion rate of 92% (95% CI: 84%-97%), and a favorable outcomes rate of 97% (95% CI: 92%-100%). Additionally, the meta-analysis demonstrated a pooled adjuvant coiling rate of 15% (95% CI: 7%-26%), a major ischemic complication rate of 1% (95% CI: 0%-2%), and a major hemorrhagic complication rate of 0% (95% CI: 0%-1%).

conclusionThe current study's findings revealed that DEDs are associated with promising complete and adequate occlusion rates concurrent with low rates of major ischemic and hemorrhagic complications.

Indexed as

DerivoDerivo embolization deviceFlow diverterIntracranial aneurysmsMeta-analysis

Identifiers

PMID40853462

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.