ArticleAnnals of hematology2025
Lymphoma and Long-Term cardiovascular disease risk: A comprehensive analysis from the UK biobank.
Article in Annals of hematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Therapeutic Targeting of the Bradykinin B2 Receptor in Immunological and Vascular Diseases: Insights from Kinin Biology to Clinical Outcomes.Clinical reviews in allergy & immunology · 2026Review
- Primary splenic diffuse large B-cell lymphoma masquerading as systemic lupus erythematosus: a case report.Frontiers in medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Lymphoma survivors may face an increased risk of cardiovascular diseases (CVDs), but large-scale studies comprehensively assessing this risk are limited. This study aims to investigate the association between lymphoma and incident CVDs, and to explore differences across lymphoma subtypes and potential effect modifiers. This retrospective cohort study used UK Biobank data. 3,244 lymphoma patients were matched 1:5 to 16,208 non-cancer controls based on demographics, lifestyle, and health factors. Incident CVDs were ascertained from electronic health records. Multivariable Cox proportional hazards regression was used to assess the association between lymphoma and each cardiovascular outcome, adjusting for key demographic, lifestyle, and clinical factors. After multivariable adjustment, lymphoma was significantly associated with increased risks of myocarditis/pericarditis (HR: 3.24, 95% CI: 2.26-4.63), heart failure/cardiomyopathy (HR: 2.65, 95% CI: 2.26-3.11), atrial fibrillation/flutter (HR: 1.80, 95% CI: 1.58-2.04), valve diseases (HR: 1.80, 95% CI: 1.47-2.19), conduction system disease (HR: 1.65, 95% CI: 1.37-1.98), supraventricular arrhythmias (HR: 1.52, 95% CI: 1.07-2.17), peripheral arterial disease (HR: 1.47, 95% CI: 1.18-1.84), and ischemic heart disease (HR: 1.18, 95% CI: 1.04-1.34). Risk varied significantly across lymphoma subtypes, with Diffuse Large B-cell Lymphoma (DLBCL) and peripheral/cutaneous T-cell lymphomas exhibiting particularly elevated risks for several outcomes. Subgroup analyses indicated that age, sex, body mass index (BMI), and hypertension status significantly modified some associations. Lymphoma is associated with a significantly increased risk of multiple CVDs. Findings highlight the need for cardiovascular risk assessment and tailored management in lymphoma survivors, considering subtype and individual risk factors.
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Registered trials
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