ArticleMikrochimica acta2025
Dual-plasmonic metals functionalized MXene synergistic enhanced SERS biosensor for sensitive and selective detection of S. aureus in milk.
Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Metagenomic characterization of the resistome, bacteriome and mobilome in raw milk from intensive farming systems.Journal of advanced research · 2026Article
- AI-Assisted Molecular Biosensors: Design Strategies for Wearable and Real-Time Monitoring.International journal of molecular sciences · 2026Review
- Advances of MXene in Detection and Sterilization of Foodborne Pathogens.Foods (Basel, Switzerland) · 2025Review
- Recognition Element-Based Strategies for Rapid Detection of Foodborne Pathogens: Recent Progress and Perspectives.Biosensors · 2025Review
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Authors and funding
7 authors.
Funding
Abstract
A multifunctional surface-enhanced Raman scattering (SERS) sensor was initially developed by integrating MXene with Au nanoparticles (MXene/Au) and plasmonic metal composite (Au@Ag NFs) as the substrate, combined with aptamers (apt) and signal molecules (4-MBA) for sensitively recognizing S. aureus in milk products. Firstly, MXene possesses the characteristic of a large specific surface area. On the one hand, it provides a higher number of attachment sites for the plasmonic metal composite, enabling the metal nanoparticles to be uniformly distributed on its surface. On the other hand, it exhibits a pre-enrichment effect for the target bacteria, remarkably enhancing the sensitivity of the SERS sensor. Secondly, Au@Ag NFs/4-MBA coupled with MXene/Au produced a synergistic electromagnetic (EM) enhancement effect, which greatly enhanced the SERS intensity and amplified the Raman signal. Furthermore, the thiol-modified aptamer (SH-apt) dramatically enhances the specificity of the SERS sensor system. Based on the sandwich-structured MXene/Au-apt-Au@Ag NFs/4-MBA, S. aureus can be detected with high sensitivity, achieving a low limit of detection of 1.009 CFU/mL and a broad linear detection range from 10 to 10
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Registered trials
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