Evidence map›Paper›PMID 40852983›Full record

ArticlemBio2025

What is the relationship between viral prospecting in animals and medical countermeasure development?

Aishani V Aatresh, Marc Lipsitch

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Aishani V AatreshHarvard College, Cambridge, Massachusetts, USA.ORCID 0000-0002-9774-2435
Marc LipsitchCenter for Communicable Disease Dynamics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.ORCID 0000-0003-1504-9213

Funding

DALHAP NAOpen Philanthropy Project NAVK Fund for CCDD NAYun Family Research Fellows Fund for Revolutionary Thinking NA
6 · The paper itself

Abstract

In recent decades, surveillance in non-human animals has aimed to detect novel viruses before they "spill over" to humans. However, the extent to which these viral prospecting efforts have enhanced outbreak preparedness remains poorly characterized, especially in terms of whether they are necessary, sufficient, or feasible to spur vaccine development. We find that several viruses which pose known threats to people lack approved vaccines, and known viruses discovered in human patients before 2000 have caused most major 21st-century outbreaks. With

Indexed as

Disease OutbreaksMedical CountermeasuresVaccine DevelopmentViral ZoonosesVirus DiseasesVirusesAnimalsHumansZoonosesEbolaMarburgmedical countermeasurespreparednessspilloversurveillancevaccinesvirus familieszoonoses

Identifiers

PMID40852983
PMCPMC12506108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.