ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2026
Impact of large-loop excision of the transformation zone on cervical morphology: A prospective observational study.
Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Determinants of Cone Volume During Large Loop Excision of the Transformation Zone (LLETZ) and Their Association with Specimen Fragmentation and Excisional Margin-A Cross-Sectional Study.Journal of clinical medicine · 2026Article
- Impact of large-loop excision of the transformation zone on cervical morphology: A prospective observational study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
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Authors and funding
5 authors.
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Abstract
objectivesTo evaluate the impact of large-loop excision of the transformation zone (LLETZ) on cervical dimensions, to identify influencing factors on cervical regeneration and to verify the concordance between ultrasonographic techniques for assessing cervical volume.
methodsThis was a prospective observational study conducted at the University of São Paulo Clinical Hospital from May 2022 to April 2023. Ultrasonographic measurements of cervical length and volume were obtained before LLETZ and at 3 and 6 months post-procedure. The influence of variables on the regenerative process was evaluated using generalized linear regression models, and the concordance between volume measurements using the cylinder formula and VOCAL (Virtual Organ Computer-Aided Analysis) software was assessed.
resultsThe mean cervical length decreased from 32.3 mm to 30.3 mm at 3 months but increased to 31.7 mm at 6 months. The volume calculated by the cylinder formula decreased from 15.6 cm
conclusionThere is a regenerative process of the cervix after LLETZ, complete in terms of length and partial in volume. The volume of the excised tissue and parity influence the regenerative process. Ultrasonographic assessments of cervical volume by two- or three-dimensional methods are comparable.
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