ArticleFrontiers in public health2025
Global burden of nasopharyngeal carcinoma attributable to alcohol use: a 1990-2021 analysis with projections to 2040.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- The global burden of alcohol-attributable cancers from 1990 to 2021: assessment and projection based on the global burden of disease study 2021.International journal of clinical oncology · 2026Article
- Targeting Ferroptosis in Nasopharyngeal Carcinoma: Mechanisms, Resistance, and Precision Therapeutic Opportunities.International journal of molecular sciences · 2025Review
- Global burden of lip and oral cavity cancer attributable to high alcohol consumption from 1990 to 2021.Frontiers in nutrition · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Nasopharyngeal carcinoma attributable to alcohol use (NPC-AU) contributes substantially to global cancer mortality and disability, yet its temporal and geographic patterns remain incompletely described. Objectives: To assess the global, regional, and national burden of NPC-AU from 1990 to 2021 and project trends through 2040. Material and methods: Using GBD 2021 data, global, regional, and national age-standardized mortality rates (ASMR) and disability-adjusted life-years rates (ASDR) attributable to alcohol were evaluated. Trends were quantified by average annual percentage change (AAPC) and projections were generated using Bayesian age-period-cohort models. Results: From 1990 to 2021, global ASMR declined from 0.31 to 0.19 per 100,000 population (AAPC -1.66; 95% CI -1.79 to -1.52) and ASDR fell with an AAPC of -1.72 (95% CI -1.87 to -1.57). Male ASMR decreased from 0.42 to 0.27 per 100,000 (AAPC -1.60), and female ASMR from 0.21 to 0.12 per 100,000 (AAPC -2.25). High-middle SDI regions saw ASMR drop from 0.50 to 0.28 per 100,000 (AAPC -1.97), whereas low-middle SDI regions experienced an increase from 0.09 to 0.11 per 100,000 (AAPC 0.72). Regionally, East Asia's ASMR declined at an AAPC of -2.70, Southern Latin America at -3.13, and Southeast Asia increased at 1.76. Age-specific peaks in ASMR shifted from 55-59 and 65-69 years in 1990 to 65-69 and 70-74 years in 2021. Projections forecast male ASMR of 0.35 per 100,000 (95% UI 0.03-0.67) and female ASMR of 0.02 per 100,000 (95% UI 0.00-0.04) by 2040. Conclusions and significance: Although global ASMR and ASDR for NPC-AU declined markedly from 1990 to 2021, rising burdens in lower-SDI regions, persistent male predominance, and shifting peaks to older age groups highlight the need for targeted alcohol-control policies and age-tailored screening.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.