Evidence map›Paper›PMID 40852597›Full record

ArticleExtracellular vesicles and circulating nucleic acids2025

Optimized size exclusion chromatography demonstrates that extracellular vesicles are the key RNA carriers of ALK translocations in non-small cell lung cancer cell line secretome and patient plasma.

Beatriz Benayas, Estela Sánchez-Herrero, Lucía Robado de Lope, Joaquín Morales, Soraya López-Martín, Mariano Provencio, Mar Valés-Gómez, Atocha Romero, María Yáñez-Mó

Abstract read
In one paragraph

Article in Extracellular vesicles and circulating nucleic acids, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Beatriz BenayasCentro de Biología Molecular Severo Ochoa (CBM), IIS-Princesa, Universidad Autónoma de Madrid, IUBM, Madrid 28049, Spain.
Estela Sánchez-HerreroImmunology and Oncology Department, Spanish National Centre for Biotechnology (CNB-CSIC), Madrid 28049, Spain.
Lucía Robado de LopeLiquid Biopsy Laboratory, Medical Oncology Department, Hospital Puerta de Hierro, IDHIPISA, Madrid 28022, Spain.
Joaquín MoralesCentro de Biología Molecular Severo Ochoa (CBM), IIS-Princesa, Universidad Autónoma de Madrid, IUBM, Madrid 28049, Spain.
Soraya López-MartínCentro de Biología Molecular Severo Ochoa (CBM), IIS-Princesa, Universidad Autónoma de Madrid, IUBM, Madrid 28049, Spain.
Mariano ProvencioLiquid Biopsy Laboratory, Medical Oncology Department, Hospital Puerta de Hierro, IDHIPISA, Madrid 28022, Spain.
Mar Valés-GómezImmunology and Oncology Department, Spanish National Centre for Biotechnology (CNB-CSIC), Madrid 28049, Spain.
Atocha RomeroLiquid Biopsy Laboratory, Medical Oncology Department, Hospital Puerta de Hierro, IDHIPISA, Madrid 28022, Spain.
María Yáñez-MóCentro de Biología Molecular Severo Ochoa (CBM), IIS-Princesa, Universidad Autónoma de Madrid, IUBM, Madrid 28049, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ALKextracellular vesiclesliquid biopsyNon-small-cell lung cancersize-exclusion chromatography

Identifiers

PMID40852597
PMCPMC12367459

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.