Evidence map›Paper›PMID 40852571›Full record

ArticleFood chemistry: X2025

A new insight into the exosome protein and lipid composition in camel colostrum and mature milk using comparative proteome and lipidomics analyses.

Liang Ming, Li Yi, Yisi Ai, Rimutu Ji

Abstract read
In one paragraph

Article in Food chemistry: X, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Liang MingCollege of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot 010018, Inner Mongolia, China.
Li YiCollege of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot 010018, Inner Mongolia, China.
Yisi AiInner Mongolia Autonomous Region International Mongolian Hospital, Hohhot 010013, Inner Mongolia, China.
Rimutu JiCollege of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot 010018, Inner Mongolia, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Camel milk exosomes from colostrum (C) and mature milk (M) were characterized using proteomics and lipidomics to elucidate their compositional and functional differences. Isolated exosomes exhibited round and cup-like concave spheres of 30 to 150 nm and higher TSG101 expression in colostrum. Proteomic analysis identified 2479 proteins, with 843 differentially expressed (357 upregulated, 486 downregulated) between C and M, enriched in PI3K-AKT signaling, endocytosis, and complement/coagulation pathways, suggesting roles in immune regulation and neonatal development. Lipidomics revealed 1783 lipid species (37 subclasses), with 149 significantly altered between C and M, including SM (d42:4; FC = 221.887) and LPE (18:3; FC = 0.139). Colostrum exosomes were enriched in sphingomyelins and glycerophospholipids, while mature milk contained higher lysophospholipids, reflecting stage-specific nutritional adaptations. These findings provide novel insights into camel milk exosome biology, highlighting their potential as biomarkers and functional food components for infant nutrition and health applications.

Indexed as

Camel milkExosomeLipidomicsProteomics

Identifiers

PMID40852571
PMCPMC12369441

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.