SynthesisFrontiers in neurology2025
Value of temporal muscle thickness in predicting outcomes of stroke: a systematic review and meta-analysis.
Synthesis in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Retrospective analysis of temporalis muscle thickness as a biomarker of functional level in adults with cerebral palsy.Journal of pediatric rehabilitation medicine · 2026Article
- Acute stroke in persons 85 years or older-clinical characteristics, impact of frailty, and predictors of outcome.Frontiers in neurology · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This systematic review examined if temporal muscle thickness (TMT) as a surrogate marker of sarcopenia was a predictor of outcomes after stroke. Methods: We explored the PubMed, Embase, Scopus, and Web of Science databases till 18th January 2025 for studies reporting stroke prognosis based on baseline TMT. Pooled analyses examined associations with post-stroke mortality, functional outcomes, and dysphagia. Meta-regression was conducted using baseline NIHSS and TMT values as moderators. Results: Nine studies were available. Meta-analysis showed that low TMT was associated with a statistically significant increase in the risk of post-stroke mortality (OR: 1.42 95% CI: 1.03, 1.96 Conclusion: Preliminary evidence suggests that lower TMT is associated with higher mortality after stroke, while associations with functional recovery remain inconclusive. Current limitations, including heterogeneity and lack of sex-specific analyses, preclude routine clinical use. Further standardized and patient-level research is warranted. Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier CRD42025637925.
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Registered trials
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