Evidence map›Paper›PMID 40852489›Full record

ArticleAlzheimer's & dementia. Behavior & socioeconomics of aging2025

Association between Trust of Researchers and Willingness to Participate in Alzheimer's Disease Biomarker Research.

Laureen Raelly-Muze, Taylor Etchison, Adele Crouch, Johanne Eliacin, Angelina Polsinelli, Sujuan Gao, Sarah Van Heiden, Joseph Asper, Caprice Elliott, Ralph Richards and 8 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia. Behavior & socioeconomics of aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Laureen Raelly-MuzeUniversity of Texas Health San Antonio, 7703 Floyd Curl Dr San Antonio, Texas, 78229 USA.
Taylor EtchisonIndiana Alzheimer's Disease Research Center, 355 W. 16th Street Indianapolis, Indiana, 46202 USA.
Adele CrouchIndiana University School of Nursing, 420 University Blvd Indianapolis, Indiana, 46202 USA.
Johanne EliacinIndiana Alzheimer's Disease Research Center, 355 W. 16th Street Indianapolis, Indiana, 46202 USA.
Angelina PolsinelliIndiana Alzheimer's Disease Research Center, 355 W. 16th Street Indianapolis, Indiana, 46202 USA.
Sujuan GaoIndiana Alzheimer's Disease Research Center, 355 W. 16th Street Indianapolis, Indiana, 46202 USA.
Sarah Van HeidenIndiana Alzheimer's Disease Research Center, 355 W. 16th Street Indianapolis, Indiana, 46202 USA.
Joseph AsperIndiana Alzheimer's Disease Research Center, 355 W. 16th Street Indianapolis, Indiana, 46202 USA.
Caprice ElliottIndiana Alzheimer's Disease Research Center, 355 W. 16th Street Indianapolis, Indiana, 46202 USA.
Ralph RichardsIndiana Alzheimer's Disease Research Center, 355 W. 16th Street Indianapolis, Indiana, 46202 USA.
Mollie RichardsIndiana Alzheimer's Disease Research Center, 355 W. 16th Street Indianapolis, Indiana, 46202 USA.
Christopher CampbellIndiana Alzheimer's Disease Research Center, 355 W. 16th Street Indianapolis, Indiana, 46202 USA.
Hugh HendrieIndiana Alzheimer's Disease Research Center, 355 W. 16th Street Indianapolis, Indiana, 46202 USA.
Pamella ShawIndiana Alzheimer's Disease Research Center, 355 W. 16th Street Indianapolis, Indiana, 46202 USA.
Omolola Adeoye-OlatundeDepartment of Pharmacy Practice, Purdue University College of Pharmacy, 640 Eskenazi Ave. Indianapolis, Indiana 46202 USA.
Shannon RisacherIndiana Alzheimer's Disease Research Center, 355 W. 16th Street Indianapolis, Indiana, 46202 USA.
Andrew SaykinIndiana Alzheimer's Disease Research Center, 355 W. 16th Street Indianapolis, Indiana, 46202 USA.
Sophia WangIndiana Alzheimer's Disease Research Center, 355 W. 16th Street Indianapolis, Indiana, 46202 USA.

Funding

Research Education ComponentP30AG010133 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI SAYKIN, ANDREW J · 1991 to 2020
$37.3M
Research Education ComponentP30AG072976 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI ANDREW J SAYKIN · 2021 to 2026
$24.1M
Memory Circuitry in MCI and Early Alzheimer’s Disease Prodrome: Molecular DriversR01AG019771 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI SAYKIN, ANDREW J · 2001 to 2021
$6.9M
Academic Leadership Award for Statistical Training in Multidisciplinary Aging ResearchK07AG076659 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI SUJUAN GAO · 2022 to 2026
$777k
NIA NIH HHS K07 AG076659NIA NIH HHS P30 AG010133NIA NIH HHS P30 AG072976NIA NIH HHS R01 AG019771
6 · The paper itself

Abstract

Introduction: The study examined the relationship between trust of researchers in research naïve participants, including those at higher risk, and interest in Alzheimer's disease and related dementia (ADRD) biomarker research participation. Methods: A cohort of 399 community-dwelling older adults completed a survey about their trust of researchers and interest in participating in ADRD biomarker research. Results: After controlling for sociodemographics and knowledge of ADRD, higher trust of researchers was associated with lower levels of hesitancy to participate in ADRD biomarker and neuroimaging studies ( Discussion: Our findings show that trust of researchers is highly correlated with research participation, independent of knowledge of ADRD and sociodemographics, and should be a focus to accelerate ADRD biomarker research participation, such as groups at higher risk.

Indexed as

Alzheimer’s diseasebiomarker research proceduresCommunity engaged researchrecruitment strategiestrust of researchers

Identifiers

PMID40852489
PMCPMC12369659

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.