Evidence map›Paper›PMID 40852476›Full record

ArticleFrontiers in oncology2025

Isolated metachronous splenic metastasis after rectal cancer surgery: a case report and literature review.

Peide Ren, Yihang Shi, Letian Zhang, Yuemin Sun, Zhibin Ye, Hengchang Liu, Shunda Wang, Yinggang Chen

Abstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Peide RenDepartment of Gastrointestinal Surgery, Cancer Hospital Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China.
Yihang ShiDepartment of Colorectal Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Letian ZhangDepartment of Colorectal Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yuemin SunDepartment of Colorectal Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zhibin YeDepartment of Gastrointestinal surgery, Hebei General Hospital, Shijiazhuang, Hebei, China.
Hengchang LiuDepartment of Colorectal Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Shunda WangDepartment of Gastrointestinal Surgery, Cancer Hospital Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China.
Yinggang ChenDepartment of Gastrointestinal Surgery, Cancer Hospital Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The occurrence of isolated splenic metastasis in association with colorectal cancer is exceedingly rare. This paper presents a case of isolated splenic metastasis identified one year after radical resection of rectal cancer. The patient underwent laparoscopic splenectomy, achieving favorable therapeutic outcomes. Furthermore, we conduct a literature review of analogous cases and examine the clinical diagnosis and therapeutic approaches for this uncommon condition. Case Review: A 76-year-old male patient underwent laparoscopic radical resection for rectal cancer, accompanied by ileostomy, at our institution. Postoperatively, the patient received two cycles of XELOX chemotherapy but continued with oral capecitabine for six cycles due to oxaliplatin intolerance. Follow-up enhanced CT scans of the chest, abdomen, and pelvis revealed an isolated metastatic tumor in the spleen. Subsequently, the patient underwent laparoscopic splenectomy. Histopathological examination post-surgery confirmed the metastasis of rectal cancer to the spleen. Conclusion: Isolated splenic metastasis originating from colorectal cancer is exceedingly rare, and laparoscopic splenectomy constitutes an effective treatment strategy.

Indexed as

colorectal cancerisolated splenic metastasislaparoscopic splenectomyliterature reviewmetachronous

Identifiers

PMID40852476
PMCPMC12367473

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.